Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SERPINC1 | P01008 | 3/20 | 0.74 |
| ▸ | F10 | P00742 | 6/20 | 0.52 |
| ▸ | FGF1 | P05230 | 4/20 | 0.51 |
| ▸ | FGF2 | P09038 | 1/20 | 0.46 |
| ▸ | F2 | P00734 | 1/20 | 0.46 |
| ▸ | HPSE | Q9Y251 | 4/20 | 0.45 |
| ▸ | BDNF | P23560 | 2/20 | 0.42 |
| ▸ | PTN | P21246 | 1/20 | 0.42 |
| ▸ | MDK | P21741 | 1/20 | 0.42 |
| ▸ | CXCL10 | P02778 | 1/20 | 0.39 |
| ▸ | CXCL8 | P10145 | 1/20 | 0.39 |
| ▸ | CCL2 | P13500 | 1/20 | 0.39 |
| ▸ | CCL5 | P13501 | 1/20 | 0.39 |
| ▸ | CXCL12 | P48061 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29407493 | 0.92 | SERPINC1 (0.85) | SERPINC1F10FGF1FGF2F2 | |
| Idraparinux SCHEMBL427808 | 0.92 | SERPINC1 (0.85) | SERPINC1F10FGF1FGF2F2 | |
| Idraparinux SCHEMBL29382311 | 0.92 | SERPINC1 (0.85) | SERPINC1F10FGF1FGF2F2 | |
| SCHEMBL12458587 | 0.87 | SERPINC1 (0.75) | SERPINC1F10FGF1FGF2F2 | |
| SCHEMBL15896273 | 0.86 | SERPINC1 (0.69) | SERPINC1F10FGF1FGF2F2 | |
| SCHEMBL12799309 | 0.84 | SERPINC1 (0.68) | SERPINC1F10FGF1FGF2F2 | |
| SCHEMBL4732494 | 0.82 | SERPINC1 (0.66) | SERPINC1F10FGF1FGF2F2 | |
| SCHEMBL13551204 | 0.82 | SERPINC1 (0.66) | SERPINC1F10FGF1FGF2F2 | |
| SCHEMBL29890443 | 0.82 | SERPINC1 (0.65) | SERPINC1F10FGF1FGF2F2 | |
| SCHEMBL16316488 | 0.82 | FGF1 (0.64) | SERPINC1F10FGF1FGF2HPSE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7919614-B2 | Disaccharide sequences formed by uronic acid and hexose as to form polysaccharides of 8-24 monosaccharide units whose hydroxyl groups are substituted by alkyl or sulphate groups; possible to modulate activities of glycosaminoglycans type | SANOFI-AVENTIS (FR) | 2011-04-05 | — | — | US | disclosed |