Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RY12 | Q9H244 | 6/20 | 0.50 |
| ▸ | P2RY2 | P41231 | 2/20 | 0.50 |
| ▸ | P2RY1 | P47900 | 2/20 | 0.50 |
| ▸ | P2RY6 | Q15077 | 1/20 | 0.50 |
| ▸ | P2RX3 | P56373 | 3/20 | 0.47 |
| ▸ | P2RX2 | Q9UBL9 | 3/20 | 0.47 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | GPR17 | Q13304 | 1/20 | 0.43 |
| ▸ | NT5E | P21589 | 1/20 | 0.43 |
| ▸ | DTYMK | P23919 | 2/20 | 0.41 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12729570 | 0.88 | SLC29A1 (0.47) | — | |
| SCHEMBL17834988 | 0.88 | SLC29A1 (0.47) | — | |
| SCHEMBL12369368 | 0.88 | P2RY12 (0.52) | P2RY12P2RY2P2RY1P2RY6P2RX3 | |
| SCHEMBL17833859 | 0.87 | POLB (0.47) | P2RY12P2RY2P2RY1P2RY6POLB | |
| SCHEMBL14183915 | 0.87 | P2RY12 (0.53) | P2RY12P2RY2P2RY1P2RY6P2RX3 | |
| SCHEMBL12369382 | 0.86 | P2RY12 (0.52) | P2RY12P2RY2P2RY1P2RY6P2RX3 | |
| SCHEMBL12729488 | 0.85 | POLB (0.54) | P2RY12P2RY2P2RY1P2RY6P2RX3 | |
| SCHEMBL17833857 | 0.82 | P2RY6 (0.43) | P2RY12P2RY2P2RY1P2RY6P2RX3 | |
| SCHEMBL21545816 | 0.80 | P2RY12 (0.64) | P2RY12P2RY2P2RY1P2RY6P2RX3 | |
| SCHEMBL30205292 | 0.80 | P2RY12 (0.64) | P2RY12P2RY2P2RY1P2RY6P2RX3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160168636-A1 | NUCLEOTIDE ANALOGS | HELICOS BIOSCIENCES CORPORATION | 2016-06-16 | — | — | US | disclosed |
| US-20160168636-A1 | NUCLEOTIDE ANALOGS | HELICOS BIOSCIENCES CORPORATION | 2016-06-16 | — | — | US | disclosed |
| US-9163053-B2 | Nucleotide analogs | FLUIDIGM CORPORATION (US) | 2015-10-20 | — | — | US | disclosed |
| US-9163053-B2 | Nucleotide analogs | FLUIDIGM CORPORATION (US) | 2015-10-20 | — | — | US | disclosed |
| US-20110081647-A1 | NUCLEOTIDE ANALOGS | HELICOS BIOSCIENCES CORPORATION (US) | 2011-04-07 | — | — | US | disclosed |
| US-20110081647-A1 | NUCLEOTIDE ANALOGS | HELICOS BIOSCIENCES CORPORATION (US) | 2011-04-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110081647-A1 | NUCLEOTIDE ANALOGS | DUT, NT5C2, NUDT21 | P2RY12 128/4885P2RY2 249/4885P2RY1 157/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.