Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | P2RY2 | P41231 | 2/20 | 0.47 |
| ▸ | P2RY6 | Q15077 | 2/20 | 0.47 |
| ▸ | P2RY4 | P51582 | 1/20 | 0.47 |
| ▸ | TAS1R3 | Q7RTX0 | 2/20 | 0.45 |
| ▸ | TAS1R1 | Q7RTX1 | 2/20 | 0.45 |
| ▸ | POLA1 | P09884 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | DTYMK | P23919 | 4/20 | 0.40 |
| ▸ | TYMP | P19971 | 1/20 | 0.39 |
| ▸ | KRAS | P01116 | 2/20 | 0.38 |
| ▸ | FUT5 | Q11128 | 1/20 | 0.38 |
| ▸ | GPR17 | Q13304 | 1/20 | 0.38 |
| ▸ | P2RY1 | P47900 | 1/20 | 0.37 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12729600 | 0.89 | POLA1 (0.52) | TAS1R3TAS1R1POLA1KDM4ETYMP | |
| SCHEMBL12729574 | 0.87 | P2RY12 (0.50) | POLBP2RY2P2RY6DTYMKGPR17 | |
| SCHEMBL12729503 | 0.86 | POLB (0.54) | POLBP2RY2P2RY6P2RY4TAS1R3 | |
| SCHEMBL17833857 | 0.83 | P2RY6 (0.43) | POLBP2RY2P2RY6P2RY4DTYMK | |
| SCHEMBL29577651 | 0.81 | TAS1R3 (0.66) | POLBP2RY2P2RY6P2RY4TAS1R3 | |
| SCHEMBL207004 | 0.78 | POLB (0.63) | POLBP2RY2P2RY6P2RY4TAS1R3 | |
| SCHEMBL17833843 | 0.78 | POLB (0.54) | POLBP2RY2P2RY6P2RY4TAS1R3 | |
| SCHEMBL12729456 | 0.77 | POLB (0.54) | POLBP2RY2P2RY6P2RY4TAS1R3 | |
| SCHEMBL12729601 | 0.77 | KDM4E (0.39) | TAS1R3TAS1R1POLA1KDM4E | |
| SCHEMBL17833841 | 0.76 | POLB (0.47) | POLBP2RY2P2RY6P2RY4DTYMK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160168636-A1 | NUCLEOTIDE ANALOGS | HELICOS BIOSCIENCES CORPORATION | 2016-06-16 | — | — | US | disclosed |
| US-20160168636-A1 | NUCLEOTIDE ANALOGS | HELICOS BIOSCIENCES CORPORATION | 2016-06-16 | — | — | US | disclosed |