SCHEMBL12730768

SCHEMBL12730768

C=COCCCCOc1ccc(C(=O)Oc2ccc(OC(=O)C3CCC4OC4C3)cc2)c(F)c1

nearest known ligand 0.35

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
▸ CRBN Q96SW2 1/20 0.35
▸ LSS P48449 4/20 0.35
▸ MEN1 O00255 1/20 0.34
▸ KMT2A Q03164 1/20 0.34
▸ PARP10 Q53GL7 2/20 0.34
▸ PARP15 Q460N3 1/20 0.34
▸ HRH3 Q9Y5N1 1/20 0.33
▸ GPR119 Q8TDV5 3/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12730709 0.86 PARP10 (0.37) CRBNLSSMEN1KMT2APARP10
SCHEMBL12730781 0.85 PRSS1 (0.39) MEN1KMT2AHRH3
SCHEMBL12730682 0.78 LSS (0.38) CRBNLSSHRH3
SCHEMBL12730661 0.77 PARP10 (0.42) CRBNLSSPARP10PARP15GPR119
SCHEMBL12730701 0.75 RARA (0.42) CRBNLSSPARP10PARP15GPR119
SCHEMBL16172295 0.74 PARP10 (0.50) CRBNLSSPARP10PARP15GPR119
SCHEMBL12730674 0.74 THRB (0.38) HRH3
SCHEMBL12730868 0.73 ELANE (0.40) MEN1KMT2A
SCHEMBL12730761 0.71 PARP15 (0.40) MEN1KMT2APARP10PARP15
SCHEMBL13829059 0.70 THRB (0.45) CRBNLSSMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8404316-B2 Polymerizable liquid crystal compound and its polymer JNC CORPORATION (JP) 2013-03-26 — — US disclosed
US-20110086185-A1 POLYMERIZABLE LIQUID CRYSTAL COMPOUND AND ITS POLYMER CHISSO CORPORATION (JP) 2011-04-14 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110086185-A1 POLYMERIZABLE LIQUID CRYSTAL COMPOUND AND ITS POLYMER CCNT1, POF1B, CCND3 CRBN 633/4885LSS 2763/4885MEN1 1805/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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