SCHEMBL1273248

SCHEMBL1273248

CC(C)CN=C(N)NCC(C)C

nearest known ligand 0.39

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
CYP2D6 P10635 1/20 0.39
CYP2C19 P33261 1/20 0.39
MMP1 P03956 1/20 0.34
MMP8 P22894 1/20 0.34
NOS1 P29475 2/20 0.34
ALDH1A1 P00352 1/20 0.33
GRIN2D O15399 1/20 0.32
GRIN3B O60391 1/20 0.32
GRIN1 Q05586 1/20 0.32
GRIN2A Q12879 1/20 0.32
GRIN2B Q13224 1/20 0.32
GRIN2C Q14957 1/20 0.32
GRIN3A Q8TCU5 1/20 0.32
SIGMAR1 Q99720 1/20 0.32
RECQL P46063 1/20 0.30
KDM4E B2RXH2 1/20 0.30
POLB P06746 1/20 0.30
CTSD P07339 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9060366 0.76
SCHEMBL21958990 0.76 CYP2D6 (0.42) CYP2D6CYP2C19MMP1MMP8RECQL
SCHEMBL4319519 0.74 CYP2D6 (0.41) CYP2D6CYP2C19MMP1MMP8RECQL
SCHEMBL4319516 0.74 CYP2D6 (0.41) CYP2D6CYP2C19MMP1MMP8RECQL
SCHEMBL18690854 0.71 CRBN (0.37) CYP2D6CYP2C19NOS1CTSD
SCHEMBL18690855 0.71 CRBN (0.37) CYP2D6CYP2C19NOS1CTSD
SCHEMBL17552353 0.70 CYP2D6 (0.37) CYP2D6CYP2C19MMP1MMP8ALDH1A1
SCHEMBL2760178 0.70 CYP2D6 (0.37) CYP2D6CYP2C19MMP1MMP8ALDH1A1
SCHEMBL1872465 0.70 CYP2D6 (0.37) CYP2D6CYP2C19MMP1MMP8
SCHEMBL1793339 0.69

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10077336-B2 Functionalized highly branched melamine-polyamine polymers BASF SE (DE) 2018-09-18 US disclosed
EP-2545123-B1 POLYAMIDES RESISTANT TO HOT AGEING BASF SE (DE) 2018-05-16 EP disclosed
US-8466221-B2 Polyamides that resist heat-aging BASF SE (DE) 2013-06-18 US disclosed
EP-2545123-A1 POLYAMIDES RESISTANT TO HOT AGEING BASF SE (DE) 2013-01-16 EP disclosed
EP-2513201-A1 FUNCTIONALIZED HIGHLY BRANCHED MELAMINE-POLYAMINE POLYMERS BASF SE (DE) 2012-10-24 EP disclosed
US-20120252987-A1 FUNCTIONALIZED HIGHLY BRANCHED MELAMINE-POLYAMINE POLYMERS BASF SE (DE) 2012-10-04 US disclosed
WO-2011128437-A1 HIGHLY BRANCHED AMINE POLYMERS AND AMINE OLIGOMERS AS CORROSION INHIBITOR BASF SE (DE) 2011-10-20 WO disclosed
US-20110257321-A1 HIGHLY BRANCHED POLYAMINES AND OLIGOAMINES AS CORROSION INHIBITORS BASF SE (DE) 2011-10-20 US disclosed
US-20110224347-A1 POLYAMIDES THAT RESIST HEAT-AGING BASF SE (DE) 2011-09-15 US disclosed
WO-2011110508-A1 POLYAMIDES RESISTANT TO HOT AGEING BASF SE (DE) 2011-09-15 WO disclosed
WO-2011073246-A1 FUNCTIONALIZED HIGHLY BRANCHED MELAMINE-POLYAMINE POLYMERS BASF SE (DE) 2011-06-23 WO disclosed
EP-2285861-A2 HYPERBRANCHED POLYMERS AND OLIGOMERS COMPRISING TERMINAL AMINO GROUPS AS CURING AGENTS FOR EPOXY RESINS BASF SE (DE) 2011-02-23 EP disclosed
US-20110028603-A1 HYPERBRANCHED POLYMERS AND OLIGOMERS COMPRISING TERMINAL AMINO GROUPS AS CURING AGENTS FOR EPOXY RESINS BASF SE (DE) 2011-02-03 US disclosed
WO-2009124998-A2 HYPERBRANCHED POLYMERS AND OLIGOMERS COMPRISING TERMINAL AMINO GROUPS AS CURING AGENTS FOR EPOXY RESINS BASF SE (DE) 2009-10-15 WO disclosed
WO-2009080787-A1 HYPERBRANCHED UREA-MELAMINE POLYMERS BASF SE (DE) 2009-07-02 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120252987-A1 FUNCTIONALIZED HIGHLY BRANCHED MELAMINE-POLYAMINE POLYMERS PARN, INMT, SRM CYP2D6 4489/4885CYP2C19 3016/4885MMP1 3323/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.