Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESRRA | P11474 | 3/20 | 0.42 |
| ▸ | MAOB | P27338 | 7/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | ATP2A2 | P16615 | 1/20 | 0.38 |
| ▸ | ATP2A3 | Q93084 | 1/20 | 0.38 |
| ▸ | MAOA | P21397 | 2/20 | 0.38 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.37 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12732650 | 0.87 | ESRRA (0.46) | ESRRAALDH1A1TSHRTDP1CYP1A2 | |
| SCHEMBL12732773 | 0.85 | ESRRA (0.49) | ESRRAMAOBALDH1A1TSHRTDP1 | |
| SCHEMBL12732571 | 0.84 | EGFR (0.40) | ESRRAMAOBALDH1A1CYP1A2SMN1; SMN2 | |
| SCHEMBL12732623 | 0.83 | LTA4H (0.53) | ESRRAALDH1A1TSHRTDP1CYP1A2 | |
| SCHEMBL12732798 | 0.82 | ESRRA (0.45) | ESRRAALDH1A1TSHRTDP1CYP1A2 | |
| SCHEMBL12733352 | 0.80 | ESRRA (0.53) | ESRRAALDH1A1TSHRTDP1CYP1A2 | |
| SCHEMBL12732654 | 0.80 | MEN1 (0.54) | ESRRAALDH1A1TSHRTDP1CYP1A2 | |
| SCHEMBL12732749 | 0.80 | HSP90AA1 (0.52) | ESRRAALDH1A1TSHRTDP1CYP1A2 | |
| SCHEMBL12732554 | 0.79 | CYP3A4 (0.45) | ESRRAALDH1A1ALOX15SMN1; SMN2CYP2C9 | |
| SCHEMBL12732777 | 0.79 | F10 (0.42) | ESRRAALDH1A1TSHRTDP1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7932283-B2 | Fungicide N-cyclopropyl-sulfonylamide derivatives | BAYER CROPSCIENCE AG (DE) | 2011-04-26 | — | — | US | disclosed |
| US-20090137611-A1 | Fungicide N-Cyclopropyl-Sulfonylamide Derivatives | BAYER CROPSCIENCE AG (DE) | 2009-05-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090137611-A1 | Fungicide N-Cyclopropyl-Sulfonylamide Derivatives | CYP51A1, ERG28, CBR3 | ESRRA 2451/4885MAOB 2906/4885ALDH1A1 2140/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.