Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VCAM1 | P19320 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 11/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | SIRT6 | Q8N6T7 | 3/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10078921 | 0.85 | VCAM1 (0.42) | VCAM1MAPTALDH1A1HTTCYP1A2 | |
| SCHEMBL4301297 | 0.82 | MAPT (0.59) | VCAM1MAPTALDH1A1HTTCYP1A2 | |
| SCHEMBL12733342 | 0.80 | MAPT (0.61) | VCAM1MAPTALDH1A1HTTCYP1A2 | |
| SCHEMBL1114152 | 0.78 | MAPT (0.60) | VCAM1MAPTALDH1A1HTTCYP1A2 | |
| SCHEMBL82777 | 0.78 | MAPT (0.60) | VCAM1MAPTALDH1A1HTTL3MBTL1 | |
| SCHEMBL16318379 | 0.75 | VCAM1 (0.50) | VCAM1MAPTALDH1A1HTTCYP1A2 | |
| SCHEMBL16318378 | 0.75 | VCAM1 (0.50) | VCAM1MAPTALDH1A1HTTCYP1A2 | |
| SCHEMBL10058378 | 0.74 | LMNA (0.46) | VCAM1MAPTALDH1A1HTTCYP1A2 | |
| SCHEMBL1114019 | 0.71 | LMNA (0.63) | MAPTALDH1A1LMNA | |
| SCHEMBL4804985 | 0.70 | KMT2A (0.47) | VCAM1MAPTALDH1A1HTTCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110098305-A1 | ARYLSULFONAMIDE COMPOUNDS, COMPOSITIONS AND METHODS OF USE | BAELL JONATHAN BAYLDON | 2011-04-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110098305-A1 | ARYLSULFONAMIDE COMPOUNDS, COMPOSITIONS AND METHODS OF USE | BAX, API5, BCL2 | VCAM1 3262/4885MAPT 4404/4885ALDH1A1 4380/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.