SCHEMBL12733763

SCHEMBL12733763

C[n+]1c(C=CC=C2C=CN(CCO)c3ccccc32)sc2ccccc21

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RAB9A P51151 8/20 0.41
HTT P42858 7/20 0.41
MAPT P10636 7/20 0.41
NPSR1 Q6W5P4 6/20 0.41
MAPK1 P28482 5/20 0.41
L3MBTL1 Q9Y468 4/20 0.41
POLB P06746 3/20 0.41
NSD2 O96028 2/20 0.41
NPC1 O15118 7/20 0.39
USP2 O75604 2/20 0.39
MTOR P42345 1/20 0.39
KMT2A Q03164 9/20 0.39
MEN1 O00255 8/20 0.39
THRB P10828 4/20 0.39
SMN1; SMN2 Q16637 3/20 0.39
TDP1 Q9NUW8 3/20 0.39
INSR P06213 1/20 0.38
BLM P54132 4/20 0.38
ADRB2 P07550 3/20 0.37
ADRB1 P08588 2/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26845473 1.00 RAB9A (0.41) RAB9AHTTMAPTNPSR1MAPK1
SCHEMBL13602010 1.00 RAB9A (0.41) RAB9AHTTMAPTNPSR1MAPK1
SCHEMBL26845472 0.96 RAB9A (0.42) RAB9AHTTMAPTNPSR1MAPK1
SCHEMBL13108258 0.89 NPC1 (0.43) RAB9AHTTMAPTNPSR1MAPK1
SCHEMBL13525403 0.89 KMT2A (0.40) RAB9AHTTMAPTNPSR1MAPK1
SCHEMBL26845348 0.89 RAB9A (0.38) RAB9AHTTMAPTNPSR1MAPK1
SCHEMBL26845349 0.89 ADRB2 (0.38) RAB9AHTTMAPTNPSR1MAPK1
SCHEMBL26845341 0.89 RAB9A (0.44) RAB9AHTTMAPTNPSR1MAPK1
SCHEMBL19654123 0.88 RAB9A (0.38) RAB9AHTTMAPTNPSR1MAPK1
SCHEMBL26845357 0.87 MEN1 (0.52) RAB9AHTTMAPTNPSR1MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 42 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2166353-B1 REAGENT AND REAGENT KIT FOR ANALYSIS OF PRIMITIVE LEUKOCYTE SYSMEX CORP (JP) 2018-08-08 EP disclosed
US-20170343537-A1 SPECIMEN ANALYZING METHOD, SPECIMEN ANALYZER, AND REAGENT SYSMEX CORPORATION (JP) 2017-11-30 US disclosed
US-9658197-B2 Standard material for a particle analyzer SYSMEX CORPORATION (JP) 2017-05-23 US disclosed
US-9658197-B2 Standard material for a particle analyzer SYSMEX CORPORATION (JP) 2017-05-23 US disclosed
US-20160202170-A1 BLOOD ANALYZER, BLOOD ANALYSIS METHOD, AND COMPUTER PROGRAM PRODUCT SYSMEX CORPORATION 2016-07-14 US disclosed
US-9222934-B2 Reagent and reagent kit for analysis of immature leukocyte SYSMEX CORPORATION (JP) 2015-12-29 US disclosed
US-9116093-B2 Blood analyzer, blood analysis method, and computer program product SYSMEX CORPORATION (JP) 2015-08-25 US disclosed
EP-1918709-B1 Analyzing method for platelets SYSMEX CORP (JP) 2015-04-01 EP disclosed
US-8859200-B2 Reagent and reagent kit for analysis of immature leukocyte SYSMEX CORPORATION (JP) 2014-10-14 US disclosed
US-20140051071-A1 BLOOD ANALYZER, BLOOD ANALYSIS METHOD, AND COMPUTER PROGRAM PRODUCT SYSMEX CORPORATION (JP) 2014-02-20 US disclosed
US-20080176274-A1 METHOD OF CLASSIFYING AND COUNTING LEUCOCYTES SYSMEX CORPORATION (JP) 2008-07-24 US disclosed
US-20080131898-A1 METHOD FOR MEASURING BIOLOGICAL SAMPLE AND MEASURING APPARATUS THEREFOR SYSMEX CORPORATION (JP) 2008-06-05 US disclosed
EP-1918709-A1 Reagent, reagent kit and analyzing method Sysmex Corporation (JP) 2008-05-07 EP disclosed
US-20080102526-A1 REAGENT, REAGENT KIT AND ANALYZING METHOD SYSMEX CORPORATION (JP) 2008-05-01 US disclosed
US-7309581-B2 Method of staining, detection and counting bacteria, and a diluent for bacterial stain SYSMEX CORPORATION (JP) 2007-12-18 US disclosed
US-20070231913-A1 Method and apparatus for measuring hematological sample SYSMEX CORPORATION (JP) 2007-10-04 US disclosed
EP-1813942-A1 Reagent for immature leukocyte analysis and reagent kit Sysmex Corporation (JP) 2007-08-01 EP disclosed
EP-1405918-B1 Bacteria counting method, bacteria counting apparatus, and reagent kit for counting bacteria SYSMEX CORP (JP) 2007-02-28 EP disclosed
US-20070013906-A1 Standard material for particle analyzer SYSMEX CORPORATION 2007-01-18 US disclosed
US-20070013906-A1 Standard material for particle analyzer SYSMEX CORPORATION 2007-01-18 US disclosed