Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NFE2L2 | Q16236 | 5/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.32 |
| ▸ | NAAA | Q02083 | 1/20 | 0.31 |
| ▸ | KDM1A | O60341 | 1/20 | 0.30 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12822843 | 0.92 | PELI1 (0.39) | NFE2L2 | |
| SCHEMBL12739544 | 0.90 | NFE2L2 (0.38) | NFE2L2HDAC1 | |
| SCHEMBL12734670 | 0.90 | NFE2L2 (0.38) | NFE2L2HDAC1 | |
| SCHEMBL13586301 | 0.90 | NFE2L2 (0.41) | NFE2L2 | |
| SCHEMBL12739590 | 0.89 | NFE2L2 (0.46) | NFE2L2HDAC1KDM1AHDAC6 | |
| SCHEMBL12734677 | 0.88 | NFE2L2 (0.44) | NFE2L2HDAC1KDM1AHDAC6 | |
| SCHEMBL10301714 | 0.87 | NFE2L2 (0.35) | NFE2L2NAAA | |
| SCHEMBL12734807 | 0.86 | NFE2L2 (0.40) | NFE2L2HDAC1KDM1AHDAC6 | |
| SCHEMBL10301769 | 0.86 | NFE2L2 (0.45) | NFE2L2HDAC1KDM1AHDAC6 | |
| SCHEMBL10302921 | 0.84 | PELI1 (0.39) | NFE2L2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8394294-B2 | Four-ring liquid crystal compound having lateral fluorine, liquid crystal composition and liquid crystal display device | JNC CORPORATION (JP) | 2013-03-12 | — | — | US | disclosed |
| US-20110090450-A1 | FOUR-RING LIQUID CRYSTAL COMPOUND HAVING LATERAL FLUORINE, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE | JNC CORPORATION (JP) | 2011-04-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110090450-A1 | FOUR-RING LIQUID CRYSTAL COMPOUND HAVING LATERAL FLUORINE, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE | LEF1, LAS1L, EFHD2 | NFE2L2 1574/4885HDAC1 2612/4885NAAA 3997/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.