Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 4/20 | 0.66 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.44 |
| ▸ | MAOB | P27338 | 1/20 | 0.43 |
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.42 |
| ▸ | EBP | Q15125 | 1/20 | 0.42 |
| ▸ | HTR2A | P28223 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | DRD2 | P14416 | 1/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.41 |
| ▸ | HTR2C | P28335 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | HTR2B | P41595 | 1/20 | 0.41 |
| ▸ | MTOR | P42345 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL643388 | 1.00 | KDM1A (0.66) | KDM1AMEN1KMT2AAKR1B1MAOB | |
| SCHEMBL31278806 | 0.88 | KDM1A (0.55) | KDM1AMEN1KMT2AMAOBSIGMAR1 | |
| SCHEMBL7441079 | 0.88 | KDM1A (0.55) | KDM1AMEN1KMT2AMAOBSIGMAR1 | |
| SCHEMBL18088758 | 0.88 | KDM1A (0.55) | KDM1AMEN1KMT2AMAOBSIGMAR1 | |
| SCHEMBL2464182 | 0.88 | KDM1A (0.55) | KDM1AMEN1KMT2AMAOBSIGMAR1 | |
| Hydrochloric Acid SCHEMBL26916642 | 0.86 | KDM1A (0.53) | KDM1AMEN1KMT2AMAOBSIGMAR1 | |
| Propane SCHEMBL27768603 | 0.82 | KDM1A (0.50) | KDM1AMEN1KMT2AMAOBSIGMAR1 | |
| SCHEMBL17988045 | 0.79 | KDM1A (1.00) | KDM1AMEN1KMT2AAKR1B1MAOB | |
| SCHEMBL578812 | 0.79 | KDM1A (0.59) | KDM1AMEN1KMT2AAKR1B1MAOB | |
| SCHEMBL1101137 | 0.79 | KDM1A (0.59) | KDM1AMEN1KMT2AAKR1B1MAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2464630-B1 | MICROBIOCIDAL HETEROCYCLES | SYNGENTA PARTICIPATIONS AG (CH) | 2016-05-25 | — | — | EP | disclosed |
| US-20130144064-A1 | MICROBIOCIDAL HETEROCYCLES | SYNGENTA CROP PROTECTION, LLC (US) | 2013-06-06 | — | — | US | disclosed |
| US-8367844-B2 | Microbiocidal heterocycles | SYNGENTA CROP PROTECTION LLC (US) | 2013-02-05 | — | — | US | disclosed |
| EP-2464630-A2 | MICROBIOCIDAL HETEROCYCLES | Syngenta Participations AG (CH) | 2012-06-20 | — | — | EP | disclosed |
| US-20120142698-A1 | MICROBIOCIDAL HETEROCYCLES | SYNGENTA CROP PROTECTION, LLC (US) | 2012-06-07 | — | — | US | disclosed |
| WO-2011018415-A2 | MICROBIOCIDAL HETEROCYCLES | SYNGENTA PARTICIPATIONS AG (CH) | 2011-02-17 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120142698-A1 | MICROBIOCIDAL HETEROCYCLES | CBR1, NOX1, CBR3 | KDM1A 1541/4885MEN1 2163/4885KMT2A 4420/4885 |
| US-20130144064-A1 | MICROBIOCIDAL HETEROCYCLES | CBR1, NOX1, CX3CR1 | KDM1A 1550/4885MEN1 2183/4885KMT2A 4365/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.