Propane

Propane

SCHEMBL27768603

CC1(N)CCc2ccccc21.CCC

nearest known ligand 0.50

Full drug profile on Sugi Atlas →

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
KDM1A O60341 5/20 0.50
MAOB P27338 1/20 0.46
HTR2A P28223 1/20 0.44
MEN1 O00255 1/20 0.44
KMT2A Q03164 1/20 0.44
SIGMAR1 Q99720 6/20 0.43
ALDH1A1 P00352 2/20 0.40
TP53 P04637 2/20 0.40
CYP1A2 P05177 1/20 0.38
CYP3A4 P08684 1/20 0.38
CYP2D6 P10635 1/20 0.38
CYP2C9 P11712 1/20 0.38
TSHR P16473 1/20 0.38
CYP2C19 P33261 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18088758 0.94 KDM1A (0.55) KDM1AMAOBHTR2AMEN1KMT2A
SCHEMBL2464182 0.94 KDM1A (0.55) KDM1AMAOBHTR2AMEN1KMT2A
SCHEMBL31278806 0.94 KDM1A (0.55) KDM1AMAOBHTR2AMEN1KMT2A
SCHEMBL7441079 0.94 KDM1A (0.55) KDM1AMAOBHTR2AMEN1KMT2A
Hydrochloric Acid SCHEMBL26916642 0.92 KDM1A (0.53) KDM1AMAOBHTR2AMEN1KMT2A
SCHEMBL643388 0.82 KDM1A (0.66) KDM1AMAOBHTR2AMEN1KMT2A
SCHEMBL1273553 0.82 KDM1A (0.66) KDM1AMAOBHTR2AMEN1KMT2A
SCHEMBL7549093 0.74 SIGMAR1 (0.44) KDM1AMAOBHTR2AMEN1KMT2A
SCHEMBL30298333 0.74 SIGMAR1 (0.44) KDM1AMAOBHTR2AMEN1KMT2A
SCHEMBL30298335 0.74 SIGMAR1 (0.44) KDM1AMAOBHTR2AMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101489984-B Aminoindan derivative or salt thereof ASTELLAS PHARMA INC 2013-04-03 CN disclosed
CN-101489984-A Aminoindan derivative or salt thereof ASTELLAS PHARMA INC (JP) 2009-07-22 CN disclosed