SCHEMBL12736724

SCHEMBL12736724

CCCCCc1ccc(-c2ccc(COC3CCC(c4ccc(OCC)c(F)c4F)CC3)c(F)c2F)cc1

nearest known ligand 0.38

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
FFAR4 Q5NUL3 7/20 0.38
NAAA Q02083 1/20 0.35
RARB P10826 1/20 0.34
SPHK1 Q9NYA1 6/20 0.33
MAPT P10636 1/20 0.32
RAB9A P51151 1/20 0.32
L3MBTL1 Q9Y468 1/20 0.32
ACE2 Q9BYF1 1/20 0.31
FGFR1 P11362 1/20 0.31
FGFR2 P21802 1/20 0.31
ALOX5AP P20292 1/20 0.30
FEN1 P39748 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12740304 1.00 FFAR4 (0.38) FFAR4NAAARARBSPHK1MAPT
SCHEMBL12740302 0.93 NAAA (0.37) FFAR4NAAAFGFR1FGFR2ALOX5AP
SCHEMBL12736719 0.93 NAAA (0.37) FFAR4NAAAFGFR1FGFR2ALOX5AP
SCHEMBL12736732 0.93 FFAR4 (0.38) FFAR4NAAARARBSPHK1
SCHEMBL12740300 0.93 FFAR4 (0.38) FFAR4NAAARARBSPHK1
SCHEMBL12733862 0.91 RARB (0.39) FFAR4RARBSPHK1MAPTRAB9A
SCHEMBL12740298 0.89 FFAR4 (0.36) FFAR4RARBSPHK1ALOX5APFEN1
SCHEMBL12736714 0.89 FFAR4 (0.36) FFAR4RARBSPHK1ALOX5APFEN1
SCHEMBL12740301 0.89 NAAA (0.38) FFAR4NAAAFGFR1FGFR2ALOX5AP
SCHEMBL12736726 0.89 NAAA (0.38) FFAR4NAAAFGFR1FGFR2ALOX5AP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8394294-B2 Four-ring liquid crystal compound having lateral fluorine, liquid crystal composition and liquid crystal display device JNC CORPORATION (JP) 2013-03-12 US disclosed
US-20110090450-A1 FOUR-RING LIQUID CRYSTAL COMPOUND HAVING LATERAL FLUORINE, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE JNC CORPORATION (JP) 2011-04-21 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110090450-A1 FOUR-RING LIQUID CRYSTAL COMPOUND HAVING LATERAL FLUORINE, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE LEF1, LAS1L, EFHD2 FFAR4 546/4885NAAA 3997/4885RARB 2705/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.