SCHEMBL1273740

SCHEMBL1273740

CCCCCCCCCCN=C(N)NCCCCCCCCCC

nearest known ligand 0.78

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GRIN2D O15399 1/20 0.78
GRIN3B O60391 1/20 0.78
GRIN1 Q05586 1/20 0.78
GRIN2A Q12879 1/20 0.78
GRIN2B Q13224 1/20 0.78
GRIN2C Q14957 1/20 0.78
GRIN3A Q8TCU5 1/20 0.78
SIGMAR1 Q99720 1/20 0.78
MEN1 O00255 3/20 0.57
KMT2A Q03164 3/20 0.57
DDAH1 O94760 2/20 0.50
CYP1A2 P05177 2/20 0.48
SMN1; SMN2 Q16637 1/20 0.48
EPHX1 P07099 4/20 0.47
USP2 O75604 1/20 0.46
LMNA P02545 1/20 0.46
TP53 P04637 1/20 0.46
CYP2D6 P10635 1/20 0.46
CYP2C9 P11712 1/20 0.46
TSHR P16473 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6015497 1.00 GRIN2D (0.78) GRIN2DGRIN3BGRIN1GRIN2AGRIN2B
SCHEMBL1273285 1.00 GRIN2D (0.78) GRIN2DGRIN3BGRIN1GRIN2AGRIN2B
SCHEMBL1273857 1.00 GRIN2D (0.78) GRIN2DGRIN3BGRIN1GRIN2AGRIN2B
SCHEMBL1272678 1.00 GRIN2D (0.78) GRIN2DGRIN3BGRIN1GRIN2AGRIN2B
SCHEMBL1272679 1.00 GRIN2D (0.78) GRIN2DGRIN3BGRIN1GRIN2AGRIN2B
SCHEMBL9757892 1.00 GRIN2D (0.78) GRIN2DGRIN3BGRIN1GRIN2AGRIN2B
SCHEMBL12099361 1.00 GRIN2D (0.78) GRIN2DGRIN3BGRIN1GRIN2AGRIN2B
SCHEMBL10487392 1.00 GRIN2D (0.78) GRIN2DGRIN3BGRIN1GRIN2AGRIN2B
Hydrochloric Acid SCHEMBL8179012 0.98 GRIN2D (0.75) GRIN2DGRIN3BGRIN1GRIN2AGRIN2B
SCHEMBL1273856 0.98 GRIN2D (0.81) GRIN2DGRIN3BGRIN1GRIN2AGRIN2B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10077336-B2 Functionalized highly branched melamine-polyamine polymers BASF SE (DE) 2018-09-18 US disclosed
EP-2545123-B1 POLYAMIDES RESISTANT TO HOT AGEING BASF SE (DE) 2018-05-16 EP disclosed
US-8466221-B2 Polyamides that resist heat-aging BASF SE (DE) 2013-06-18 US disclosed
EP-2545123-A1 POLYAMIDES RESISTANT TO HOT AGEING BASF SE (DE) 2013-01-16 EP disclosed
EP-2513201-A1 FUNCTIONALIZED HIGHLY BRANCHED MELAMINE-POLYAMINE POLYMERS BASF SE (DE) 2012-10-24 EP disclosed
US-20120252987-A1 FUNCTIONALIZED HIGHLY BRANCHED MELAMINE-POLYAMINE POLYMERS BASF SE (DE) 2012-10-04 US disclosed
WO-2011128437-A1 HIGHLY BRANCHED AMINE POLYMERS AND AMINE OLIGOMERS AS CORROSION INHIBITOR BASF SE (DE) 2011-10-20 WO disclosed
US-20110257321-A1 HIGHLY BRANCHED POLYAMINES AND OLIGOAMINES AS CORROSION INHIBITORS BASF SE (DE) 2011-10-20 US disclosed
WO-2011110508-A1 POLYAMIDES RESISTANT TO HOT AGEING BASF SE (DE) 2011-09-15 WO disclosed
US-20110224347-A1 POLYAMIDES THAT RESIST HEAT-AGING BASF SE (DE) 2011-09-15 US disclosed
WO-2011073246-A1 FUNCTIONALIZED HIGHLY BRANCHED MELAMINE-POLYAMINE POLYMERS BASF SE (DE) 2011-06-23 WO disclosed
EP-2285861-A2 HYPERBRANCHED POLYMERS AND OLIGOMERS COMPRISING TERMINAL AMINO GROUPS AS CURING AGENTS FOR EPOXY RESINS BASF SE (DE) 2011-02-23 EP disclosed
US-20110028603-A1 HYPERBRANCHED POLYMERS AND OLIGOMERS COMPRISING TERMINAL AMINO GROUPS AS CURING AGENTS FOR EPOXY RESINS BASF SE (DE) 2011-02-03 US disclosed
WO-2009124998-A2 HYPERBRANCHED POLYMERS AND OLIGOMERS COMPRISING TERMINAL AMINO GROUPS AS CURING AGENTS FOR EPOXY RESINS BASF SE (DE) 2009-10-15 WO disclosed
WO-2009080787-A1 HYPERBRANCHED UREA-MELAMINE POLYMERS BASF SE (DE) 2009-07-02 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120252987-A1 FUNCTIONALIZED HIGHLY BRANCHED MELAMINE-POLYAMINE POLYMERS PARN, INMT, SRM GRIN2D 4620/4885GRIN3B 4127/4885GRIN1 4055/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.