Known targets — ChEMBL curated mechanism
ADRA2AADRA2BADRA2CADRB2AGTR1AVPR1AAVPR1BAVPR2BDKRB2CALCRCHRNA3CHRNB4ESR1ESR2GHSRGNRHRGSC1HSPA8MALT1MC1RMC4RNOS1NOS2NOS3OPRK1OXTRRAMP1RAMP2RAMP3SCN5ASSTR1SSTR2SSTR3SSTR4SSTR5dacAdacBdacCfolPftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Acetic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 known ✓ | P03372 | 1/20 | 0.46 |
| ▸ | ESR2 known ✓ | Q92731 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 3/20 | 0.59 |
| ▸ | TP53 | P04637 | 1/20 | 0.59 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.56 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 4/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.53 |
| ▸ | NPC1 | O15118 | 3/20 | 0.53 |
| ▸ | HTT | P42858 | 2/20 | 0.53 |
| ▸ | RAB9A | P51151 | 2/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | F2 | P00734 | 1/20 | 0.52 |
| ▸ | CA12 | O43570 | 1/20 | 0.47 |
| ▸ | CA1 | P00915 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 1/20 | 0.47 |
| ▸ | CA7 | P43166 | 1/20 | 0.47 |
| ▸ | CA9 | Q16790 | 1/20 | 0.47 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6660758 | 0.96 | TSHR (0.63) | TSHRTP53PDCD1CD274LMNA | |
| SCHEMBL5986325 | 0.92 | TSHR (0.55) | TSHRTP53PDCD1CD274LMNA | |
| SCHEMBL12922990 | 0.92 | TSHR (0.55) | TSHRTP53PDCD1CD274LMNA | |
| SCHEMBL3960239 | 0.90 | TSHR (0.57) | TSHRTP53PDCD1CD274LMNA | |
| SCHEMBL1344718 | 0.89 | TSHR (0.52) | TSHRTP53PDCD1CD274LMNA | |
| SCHEMBL1344826 | 0.89 | TSHR (0.52) | TSHRTP53PDCD1CD274LMNA | |
| SCHEMBL1345799 | 0.89 | TSHR (0.52) | TSHRTP53PDCD1CD274LMNA | |
| SCHEMBL3397611 | 0.88 | TSHR (0.55) | TSHRTP53PDCD1CD274LMNA | |
| SCHEMBL5152870 | 0.86 | CA12 (0.67) | TSHRTP53PDCD1CD274LMNA | |
| SCHEMBL4418738 | 0.86 | TSHR (0.57) | TSHRTP53PDCD1CD274LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 116 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0565017-B1 | Liquid bleach and detergent compositions | SOLVAY INTEROX LTD (GB) | 1999-07-07 | — | — | EP | claimed |
| US-5458802-A | Sodium superborate | SOLVAY INTEROX LIMITED (GB) | 1995-10-17 | — | — | US | claimed |
| EP-0565017-A2 | Liquid bleach and detergent compositions | SOLVAY INTEROX LIMITED (GB) | 1993-10-13 | — | — | EP | claimed |
| EP-0125781-B1 | PEROXYGEN COMPOUNDS | Interox Chemicals Limited (GB) | 1987-08-12 | — | — | EP | claimed |
| EP-0122763-B1 | BLEACH COMPOSITIONS | Interox Chemicals Limited (GB) | 1987-06-16 | — | — | EP | claimed |
| US-4545784-A | LOW-TEMPERATURE ACTIVATED BLEACHES; LAUNDERING; ANTISEPTICS; STORAGE STABILITY | INTEROX CHEMICALS LIMITED (GB) | 1985-10-08 | — | — | US | claimed |
| US-4541944-A | BLEACHES, LAUNDRY | INTEROX CHEMICALS LIMITED (GB) | 1985-09-17 | — | — | US | claimed |
| EP-0125781-A1 | Peroxygen compounds | Interox Chemicals Limited (GB) | 1984-11-21 | — | — | EP | claimed |
| EP-0122763-A2 | Bleach compositions | Interox Chemicals Limited (GB) | 1984-10-24 | — | — | EP | claimed |
| EP-2458989-B1 | IN SITU PREPARATION OF PERACID-BASED REMOVABLE ANTIMICROBIAL COATING COMPOSITIONS AND METHODS OF USE | DU PONT (US) | 2013-10-09 | — | — | EP | disclosed |
| EP-2458989-A2 | IN SITU PREPARATION OF PERACID-BASED REMOVABLE ANTIMICROBIAL COATING COMPOSITIONS AND METHODS OF USE | E. I. du Pont de Nemours and Company (US) | 2012-06-06 | — | — | EP | disclosed |
| US-20110177145-A1 | IN SITU PREPARATION OF PERACID-BASED REMOVABLE ANTIMICROBIAL COATING COMPOSITIONS AND METHODS OF USE | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2011-07-21 | — | — | US | disclosed |
| WO-2011017087-A2 | IN SITU PREPARATION OF PERACID-BASED REMOVABLE ANTIMICROBIAL COATING COMPOSITIONS AND METHODS OF USE | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2011-02-10 | — | — | WO | disclosed |
| EP-1438380-A4 | HIGH RETENTION SANITIZER SYSTEMS | FMC CORP (US) | 2004-12-08 | — | — | EP | disclosed |
| US-4541944-A | BLEACHES, LAUNDRY | INTEROX CHEMICALS LIMITED (GB) | 1985-09-17 | — | — | US | disclosed |
| US-4541944-A | BLEACHES, LAUNDRY | INTEROX CHEMICALS LIMITED (GB) | 1985-09-17 | — | — | US | disclosed |
| EP-0125781-A1 | Peroxygen compounds | Interox Chemicals Limited (GB) | 1984-11-21 | — | — | EP | disclosed |
| EP-0125781-A1 | Peroxygen compounds | Interox Chemicals Limited (GB) | 1984-11-21 | — | — | EP | disclosed |
| EP-0122763-A2 | Bleach compositions | Interox Chemicals Limited (GB) | 1984-10-24 | — | — | EP | disclosed |
| EP-0122763-A2 | Bleach compositions | Interox Chemicals Limited (GB) | 1984-10-24 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110177145-A1 | IN SITU PREPARATION OF PERACID-BASED REMOVABLE ANTIMICROBIAL COATING COMPOSITIONS AND METHODS OF USE | VMA21, SPOUT1, SI | ESR1 869/4885ESR2 1578/4885TSHR 4153/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.