Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 6/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 4/20 | 0.48 |
| ▸ | HPGD | P15428 | 4/20 | 0.48 |
| ▸ | GAA | P10253 | 3/20 | 0.48 |
| ▸ | TSHR | P16473 | 3/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 5/20 | 0.43 |
| ▸ | MEN1 | O00255 | 8/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.42 |
| ▸ | MAPT | P10636 | 7/20 | 0.42 |
| ▸ | USP2 | O75604 | 3/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | PDE5A | O76074 | 3/20 | 0.41 |
| ▸ | POLB | P06746 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 4/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12737989 | 0.93 | HSD17B10 (0.48) | HSD17B10ALDH1A1KDM4EALOX15HPGD | |
| SCHEMBL12738233 | 0.93 | ALDH1A1 (0.53) | HSD17B10ALDH1A1KDM4EALOX15HPGD | |
| SCHEMBL12738588 | 0.91 | ALDH1A1 (0.47) | HSD17B10ALDH1A1KDM4EALOX15HPGD | |
| SCHEMBL12738229 | 0.89 | ALDH1A1 (0.47) | HSD17B10ALDH1A1KDM4EALOX15HPGD | |
| SCHEMBL12738612 | 0.85 | MAPT (0.52) | HSD17B10ALDH1A1KDM4EHPGDGAA | |
| SCHEMBL1609539 | 0.85 | HSD17B10 (0.47) | HSD17B10ALDH1A1KDM4EALOX15HPGD | |
| SCHEMBL13769657 | 0.82 | MAPT (0.46) | HSD17B10ALDH1A1KDM4EALOX15HPGD | |
| SCHEMBL12738606 | 0.82 | ALDH1A1 (0.45) | HSD17B10ALDH1A1KDM4EALOX15HPGD | |
| SCHEMBL1610779 | 0.78 | KDM4E (0.47) | HSD17B10ALDH1A1KDM4EALOX15HPGD | |
| SCHEMBL12737997 | 0.77 | LMNA (0.44) | HSD17B10ALDH1A1KDM4EHPGDGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110086759-A1 | CHEMICAL COMPOUNDS | SYNGENTA CROP PROTECTION, INC. (US) | 2011-04-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110086759-A1 | CHEMICAL COMPOUNDS | DDT, PNPO, CBR3 | HSD17B10 1869/4885ALDH1A1 1562/4885KDM4E 2613/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.