Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 2/20 | 0.45 |
| ▸ | GHSR | Q92847 | 1/20 | 0.37 |
| ▸ | SOS1 | Q07889 | 2/20 | 0.36 |
| ▸ | ITGB2 | P05107 | 1/20 | 0.36 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.36 |
| ▸ | ITGAL | P20701 | 1/20 | 0.36 |
| ▸ | KRAS | P01116 | 1/20 | 0.36 |
| ▸ | NR3C1 | P04150 | 7/20 | 0.36 |
| ▸ | BBOX1 | O75936 | 2/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.35 |
| ▸ | PGR | P06401 | 1/20 | 0.35 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | STAT3 | P40763 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1609942 | 0.72 | TDP1 (0.49) | ITGB2ICAM1ITGALNR3C1BBOX1 | |
| SCHEMBL1609510 | 0.71 | TDP1 (0.61) | BBOX1SMN1; SMN2MEN1MAPTKMT2A | |
| SCHEMBL1610962 | 0.71 | TDP1 (0.48) | ITGB2ICAM1ITGALNR3C1BBOX1 | |
| SCHEMBL1610959 | 0.71 | TDP1 (0.48) | ITGB2ICAM1ITGALNR3C1BBOX1 | |
| SCHEMBL12085748 | 0.70 | CTSL (0.58) | CTSLSLC6A4SMN1; SMN2MEN1MAPT | |
| SCHEMBL9728200 | 0.70 | CTSL (0.62) | CTSLSLC6A4SMN1; SMN2MEN1MAPT | |
| SCHEMBL15722175 | 0.70 | CTSL (0.62) | CTSLSLC6A4SMN1; SMN2MEN1MAPT | |
| SCHEMBL12126312 | 0.70 | CTSL (0.62) | CTSLSLC6A4SMN1; SMN2MEN1MAPT | |
| SCHEMBL14532871 | 0.70 | CTSL (0.63) | CTSLSLC6A4SMN1; SMN2MEN1MAPT | |
| SCHEMBL13458539 | 0.68 | CTSL (0.50) | CTSLNR3C1PGRNR3C2SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110086759-A1 | CHEMICAL COMPOUNDS | SYNGENTA CROP PROTECTION, INC. (US) | 2011-04-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110086759-A1 | CHEMICAL COMPOUNDS | DDT, PNPO, CBR3 | CTSL 4603/4885GHSR 1732/4885SOS1 355/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.