Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 2/20 | 0.62 |
| ▸ | HTR2A | P28223 | 4/20 | 0.55 |
| ▸ | HTR1A | P08908 | 2/20 | 0.55 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.55 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.55 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.55 |
| ▸ | HTR1D | P28221 | 1/20 | 0.55 |
| ▸ | HTR1B | P28222 | 1/20 | 0.55 |
| ▸ | HTR2C | P28335 | 1/20 | 0.55 |
| ▸ | HTR1E | P28566 | 1/20 | 0.55 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.55 |
| ▸ | HTR7 | P34969 | 1/20 | 0.55 |
| ▸ | HTR2B | P41595 | 1/20 | 0.55 |
| ▸ | HTR6 | P50406 | 1/20 | 0.55 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 3/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.54 |
| ▸ | POLB | P06746 | 2/20 | 0.54 |
| ▸ | APAF1 | O14727 | 1/20 | 0.54 |
| ▸ | RECQL | P46063 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12126312 | 1.00 | CTSL (0.62) | CTSLHTR2AHTR1AADRB1ADRA2A | |
| SCHEMBL15722175 | 1.00 | CTSL (0.62) | CTSLHTR2AHTR1AADRB1ADRA2A | |
| SCHEMBL14532871 | 0.88 | CTSL (0.63) | CTSLHTR2AHTR1AADRB1ADRA2A | |
| SCHEMBL4407946 | 0.86 | CTSL (0.63) | CTSLHTR2AHTR1AADRB1ADRA2A | |
| SCHEMBL180565 | 0.86 | CTSL (0.60) | CTSLHTR2AHTR1AADRB1ADRA2A | |
| SCHEMBL16190432 | 0.85 | CTSL (0.60) | CTSLHTR2AHTR1AADRB1ADRA2A | |
| SCHEMBL14534876 | 0.85 | CTSL (0.60) | CTSLHTR2AHTR1AADRB1ADRA2A | |
| SCHEMBL14532875 | 0.85 | CTSL (0.60) | CTSLHTR2AHTR1AADRB1ADRA2A | |
| SCHEMBL10063640 | 0.85 | CTSL (0.64) | CTSLHTR2AHTR1AADRB1ADRA2A | |
| SCHEMBL16562989 | 0.84 | CTSL (0.71) | CTSLMAPTKDM4EPOLBAPAF1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5140009-A | Stable against proteolytic enzymes; anticarcinogenic agents; urogenital disorders | TAP PHARMACEUTICALS, INC. (US) | 1992-08-18 | — | — | US | claimed |