Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AOC3 | Q16853 | 1/20 | 0.44 |
| ▸ | CDC7 | O00311 | 1/20 | 0.44 |
| ▸ | DBF4 | Q9UBU7 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.44 |
| ▸ | RELA | Q04206 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | LDHA | P00338 | 2/20 | 0.43 |
| ▸ | LDHB | P07195 | 1/20 | 0.43 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.42 |
| ▸ | CTSA | P10619 | 1/20 | 0.42 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.41 |
| ▸ | DAGLA | Q9Y4D2 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.40 |
| ▸ | PPID | Q08752 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2592720 | 0.79 | HTR7 (0.56) | SMN1; SMN2NPC1PKMNFKB1RAB9A | |
| SCHEMBL4556815 | 0.79 | SMN1; SMN2 (0.56) | AOC3SMN1; SMN2NPC1PKMNFKB1 | |
| SCHEMBL1275937 | 0.78 | HTT (0.44) | L3MBTL1MAPTTHRBSHMT1SHMT2 | |
| SCHEMBL68412 | 0.78 | L3MBTL1 (0.50) | SMN1; SMN2NPC1PKMNFKB1RAB9A | |
| SCHEMBL406058 | 0.77 | MAOB (0.58) | SMN1; SMN2MAOBMAPTALDH1A1LMNA | |
| SCHEMBL26646147 | 0.77 | L3MBTL1 (0.45) | SMN1; SMN2NPC1PKMNFKB1RAB9A | |
| SCHEMBL9289949 | 0.77 | BCL2 (0.42) | AOC3CTSADAGLATHRATHRB | |
| SCHEMBL1274044 | 0.76 | CTSA (0.52) | CDC7DBF4SMN1; SMN2CTSADAGLA | |
| SCHEMBL31225595 | 0.76 | L3MBTL1 (0.48) | SMN1; SMN2NPC1PKMNFKB1RAB9A | |
| SCHEMBL11850460 | 0.76 | SMN1; SMN2 (0.54) | SMN1; SMN2NPC1PKMNFKB1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2462124-B9 | MESOIONIC PESTICIDES | DU PONT (US) | 2017-08-23 | — | — | EP | disclosed |
| US-9596856-B2 | Mesoionic pesticides | E I DU PONT DE NEMOURS AND COMPANY (US) | 2017-03-21 | — | — | US | disclosed |
| US-20160066577-A1 | MESOIONIC PESTICIDES | FMC CORPORATION | 2016-03-10 | — | — | US | disclosed |
| US-9210932-B2 | Mesoionic pesticides | E I DU PONT DE NEMOURS AND COMPANY (US) | 2015-12-15 | — | — | US | disclosed |
| US-20140206536-A1 | MESOIONIC PESTICIDES | E I DU PONT DE NEMOURS AND COMPANY (US) | 2014-07-24 | — | — | US | disclosed |
| US-8722690-B2 | Mesoionic pesticides | E I DU PONT DE NEMOURS AND COMPANY (US) | 2014-05-13 | — | — | US | disclosed |
| EP-2462124-B1 | MESOIONIC PESTICIDES | DU PONT (US) | 2014-01-08 | — | — | EP | disclosed |
| US-20120277100-A1 | MESOIONIC PESTICIDES | FMC CORPORATION | 2012-11-01 | — | — | US | disclosed |
| EP-2462124-A2 | MESOIONIC PESTICIDES | E. I. du Pont de Nemours and Company (US) | 2012-06-13 | — | — | EP | disclosed |
| WO-2011017342-A2 | MESOIONIC PESTICIDES | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2011-02-10 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140206536-A1 | MESOIONIC PESTICIDES | CHRM3, CHRM2, CHRM5 | AOC3 59/4885CDC7 1736/4885DBF4 2435/4885 |
| US-20160066577-A1 | MESOIONIC PESTICIDES | CHRM3, CHRM2, CHRM5 | AOC3 59/4885CDC7 1736/4885DBF4 2435/4885 |
| US-20120277100-A1 | MESOIONIC PESTICIDES | CHRM3, CHRM2, CHRM5 | AOC3 59/4885CDC7 1664/4885DBF4 2413/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.