SCHEMBL12744414

SCHEMBL12744414

Cn1c(=O)c(C(=O)c2ccccc2)c2c3c(c(Nc4ccc(S(=O)(=O)O)cc4S(=O)(=O)O)ccc31)C(=O)c1ccccc1-2

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAP3K5 Q99683 2/20 0.54
PABPC1 P11940 3/20 0.46
MEN1 O00255 7/20 0.41
KMT2A Q03164 7/20 0.41
POLB P06746 4/20 0.41
L3MBTL1 Q9Y468 2/20 0.41
MAPT P10636 4/20 0.41
SMN1; SMN2 Q16637 1/20 0.41
NR4A1 P22736 1/20 0.40
USP2 O75604 3/20 0.37
ALDH1A1 P00352 2/20 0.37
KDM4E B2RXH2 2/20 0.37
KEAP1 Q14145 1/20 0.37
NFE2L2 Q16236 1/20 0.37
CYP1A2 P05177 3/20 0.36
MAPK1 P28482 3/20 0.36
CYP2C19 P33261 2/20 0.36
TSHR P16473 1/20 0.36
CYP3A4 P08684 1/20 0.36
CYP2C9 P11712 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL141394 0.95 MAP3K5 (0.50) MAP3K5PABPC1MEN1KMT2APOLB
SCHEMBL13400398 0.93 PABPC1 (0.47) MAP3K5PABPC1MEN1KMT2APOLB
SCHEMBL16454201 0.92 MAP3K5 (0.48) MAP3K5PABPC1MEN1KMT2APOLB
SCHEMBL17808497 0.92 MAP3K5 (0.47) MAP3K5PABPC1MEN1KMT2APOLB
SCHEMBL17808471 0.92 MAP3K5 (0.47) MAP3K5PABPC1MEN1KMT2APOLB
SCHEMBL17808486 0.91 MAP3K5 (0.43) MAP3K5PABPC1MEN1KMT2APOLB
SCHEMBL17808472 0.90 MAP3K5 (0.43) MAP3K5PABPC1MEN1KMT2APOLB
SCHEMBL17808504 0.90 MAP3K5 (0.48) MAP3K5PABPC1MEN1KMT2APOLB
SCHEMBL16454202 0.89 MAP3K5 (0.42) MAP3K5PABPC1MEN1KMT2APOLB
SCHEMBL13245821 0.89 MAP3K5 (0.45) MAP3K5PABPC1MEN1KMT2APOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3225663-A1 COLORING COMPOSITION FOR DYEING, COLORING COMPOSITION FOR PRINTING, PRINTING METHOD, INKJET PRINTING INK, AND DYED FABRIC Fujifilm Corporation (JP) 2017-10-04 EP disclosed
US-20170247544-A1 COLORING COMPOSITION FOR TEXTILE PRINTING, TEXTILE PRINTING METHOD, INK FOR INK JET TEXTILE PRINTING, AND DYED FABRIC FUJIFILM CORPORATION (JP) 2017-08-31 US disclosed
US-9011589-B2 Magenta dyes and their preparation methods and applications DALIAN UNIVERSITY OF TECHNOLOGY (CN) 2015-04-21 US disclosed
US-8734580-B2 Carbonyl propyl sulfuryl anthrapyridone sulfonic acid compounds and their preparation methods and applications DALIAN UNIVERSITY OF TECHNOLOGY (CN) 2014-05-27 US disclosed
US-20130276667-A1 CARBONYL PROPYL SULFURYL ANTHRAPYRIDONE SULFONIC ACID COMPOUNDS AND THEIR PREPARATION METHODS AND APPLICATIONS Zhuhai Ninestar Management Co., Ltd. (CN) 2013-10-24 US disclosed
US-7909926-B2 Ink composition and colored product NIPPON KAYAKU KABUSHIKI KAISHA (JP) 2011-03-22 US disclosed
US-7909926-B2 Ink composition and colored product NIPPON KAYAKU KABUSHIKI KAISHA (JP) 2011-03-22 US disclosed
US-20090324900-A1 INK COMPOSITION AND COLORED PRODUCT NIPPON KAYAKU KABUSHIKI KAISHA (JP) 2009-12-31 US disclosed
US-20090324900-A1 INK COMPOSITION AND COLORED PRODUCT NIPPON KAYAKU KABUSHIKI KAISHA (JP) 2009-12-31 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090324900-A1 INK COMPOSITION AND COLORED PRODUCT ATXN2, IK, AURKA MAP3K5 67/4885PABPC1 1856/4885MEN1 3144/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.