Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | ABL1 | P00519 | 2/20 | 0.42 |
| ▸ | GSK3A | P49840 | 2/20 | 0.42 |
| ▸ | GSK3B | P49841 | 2/20 | 0.42 |
| ▸ | ACVR1 | Q04771 | 2/20 | 0.42 |
| ▸ | CLK4 | Q9HAZ1 | 2/20 | 0.42 |
| ▸ | JAK2 | O60674 | 1/20 | 0.42 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.42 |
| ▸ | RET | P07949 | 1/20 | 0.42 |
| ▸ | JAK3 | P52333 | 1/20 | 0.42 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.42 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.42 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.42 |
| ▸ | CDK8 | P49336 | 1/20 | 0.42 |
| ▸ | CLK2 | P49760 | 1/20 | 0.42 |
| ▸ | TYRO3 | Q06418 | 1/20 | 0.42 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | SMARCA2 | P51531 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL826349 | 0.84 | LOXL2 (0.52) | GAASMARCA2SMARCA4LOXL2LOX | |
| Hydrochloric Acid SCHEMBL3745557 | 0.82 | LOXL2 (0.53) | GAASMARCA2SMARCA4LOXL2LOX | |
| SCHEMBL29447907 | 0.82 | CYP3A4 (0.64) | CYP3A4TSHRIDH1IDH2 | |
| SCHEMBL119701 | 0.82 | CYP3A4 (0.64) | CYP3A4TSHRIDH1IDH2 | |
| SCHEMBL28202386 | 0.81 | CYP3A4 (0.50) | CYP3A4TSHRGAATGFBR1GRM5 | |
| SCHEMBL27112635 | 0.74 | ACVR1 (0.50) | ABL1GSK3AGSK3BACVR1CLK4 | |
| Bicarbonate SCHEMBL28211551 | 0.71 | CYP3A4 (0.55) | CYP3A4TSHRABL1GSK3AGSK3B | |
| SCHEMBL16369760 | 0.70 | LOXL2 (0.36) | SMARCA2SMARCA4IDH1LOXL2LOX | |
| SCHEMBL31543170 | 0.70 | LOXL2 (0.36) | SMARCA2SMARCA4IDH1LOXL2LOX | |
| SCHEMBL29850129 | 0.69 | LOXL2 (0.37) | GAASMARCA2SMARCA4LOXL2LOX |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2462124-A2 | MESOIONIC PESTICIDES | E. I. du Pont de Nemours and Company (US) | 2012-06-13 | — | — | EP | disclosed |
| WO-2011017342-A2 | MESOIONIC PESTICIDES | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2011-02-10 | — | — | WO | disclosed |