Trifluoroacetic Acid

Trifluoroacetic Acid

SCHEMBL1274530

O=C(O)C(F)(F)F.Oc1c(F)c(F)c(F)c(F)c1F

nearest known ligand 0.42

Full drug profile on Sugi Atlas →

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
CES1 P23141 1/20 0.32
ESR1 P03372 1/20 0.31
ALDH1A1 P00352 1/20 0.31
L3MBTL1 Q9Y468 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Bicarbonate SCHEMBL10006506 0.82 CA1 (0.36) CES1ESR1
Trifluoroacetic Acid SCHEMBL5903486 0.80 CA1 (0.41) CES1ALDH1A1
Trifluoroacetic Acid SCHEMBL31659099 0.78
Trifluoroacetic Acid SCHEMBL30509267 0.78 ALDH1A1 (0.42) CES1ALDH1A1L3MBTL1
Acetic Acid SCHEMBL3565472 0.77 FFAR3 (0.44) ESR1
Trifluoroacetic Acid SCHEMBL3855786 0.76 CES1 (0.31) CES1
Trifluoroacetic Acid SCHEMBL28890383 0.76 MEN1 (0.36) CES1
Trifluoroacetic Acid SCHEMBL4598430 0.74
Trifluoroacetic Acid SCHEMBL2484766 0.74 ALDH1A1 (0.44) CES1ALDH1A1L3MBTL1
SCHEMBL34203 0.74 ESR1 (0.31) ESR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 115 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116904532-A Method for synthesizing novel chiral polyamide by cutinase catalysis 浙江农林大学暨阳学院 2023-10-20 CN claimed
CN-113461519-A Preparation method of octadecanedioic acid mono-tert-butyl ester-PFP 浙江泽瑞生物医药有限公司 2021-10-01 CN claimed
US-4978744-A Synthesis of dolastatin 10 ARIZONA BOARD OF REGENTS (US) 1990-12-18 US claimed
CN-122056912-A Application of siRNA in preparing medicament for treating hepatitis 苏州星曜坤泽生物制药有限公司 2026-05-19 CN disclosed
US-20250277211-A1 LPA inhibitors and uses thereof KYLONOVA XIAMEN BIOPHARMA CO LTD (CN) 2025-09-04 US disclosed
EP-4610356-A1 RNA INHIBITOR FOR INHIBITING LPA GENE EXPRESSION AND USE THEREOF Kylonova (Xiamen) Biopharma Co., Ltd. (CN) 2025-09-03 EP disclosed
EP-4567112-A1 RNA INHIBITOR FOR INHIBITING APOC3 GENE EXPRESSION AND USE THEREOF Kylonova (Xiamen) Biopharma Co., Ltd. (CN) 2025-06-11 EP disclosed
WO-2025111500-A1 MODULATION OF GENE EXPRESSION IONIS PHARMACEUTICALS, INC. (US) 2025-05-30 WO disclosed
CN-113862268-B AGT inhibitors and uses thereof 厦门甘宝利生物医药有限公司 2025-05-13 CN disclosed
CN-119925624-A Liver targeting compound and conjugate, preparation method and application thereof 上海数因信科智能科技有限公司 2025-05-06 CN disclosed
WO-2025064427-A1 DUAL-PAYLOAD ANTIBODY-DRUG CONJUGATES AND USES THEREOF R.P. SCHERER TECHNOLOGIES, LLC (US) 2025-03-27 WO disclosed
US-5654282-A Selectin binding glycopeptides GLYCOMED INCORPORATED (US) 1997-08-05 US disclosed
EP-0720619-A1 SELECTIN BINDING GLYCOPEPTIDES GLYCOMED INCORPORATED (US) 1996-07-10 EP disclosed
US-5508387-A Selectin binding glycopeptides GLYCOMED INCORPORATED (US) 1996-04-16 US disclosed
WO-1995004751-A1 SELECTIN BINDING GLYCOPEPTIDES GLYCOMED INCORPORATED (US) 1995-02-16 WO disclosed
US-4978744-A Synthesis of dolastatin 10 ARIZONA BOARD OF REGENTS (US) 1990-12-18 US disclosed
US-4851503-A UNAITS OF 4-OXYBENZOYL, TEREPHTHALOYL, 4,4'-DIOXYBIPHENYL, 4,4'-DIOXYDIPHENYL ETHER; FORMS; FILMS; FIBERS; SEALS KURARAY COMPANY, LTD. (JP) 1989-07-25 US disclosed
US-4837268-A TEREPHTHALIC ACID, DIHYDROXYDIPHENYL ETHER, P-HYDROXYBENZOIC ACID; THERMOTROPIC LIQUID CRYSTAL KURARAY COMPANY, LTD. (JP) 1989-06-06 US disclosed
EP-0273424-A2 Aromatic polyesters and their use KURARAY CO., LTD. (JP) 1988-07-06 EP disclosed
EP-0273423-A2 Aromatic polyesters and their use KURARAY CO., LTD. (JP) 1988-07-06 EP disclosed