Trifluoroacetic Acid

Trifluoroacetic Acid

SCHEMBL2484766

O=C(O)C(F)(F)F.O=C(O)C(F)(F)F

nearest known ligand 0.44

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.44
L3MBTL1 Q9Y468 1/20 0.44
TSHR P16473 2/20 0.43
TP53 P04637 1/20 0.43
THRB P10828 1/20 0.42
CA2 P00918 2/20 0.41
CES1 P23141 2/20 0.38
ACLY P53396 2/20 0.36
CA1 P00915 1/20 0.36
CA9 Q16790 1/20 0.36
POLB P06746 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
TET2 Q6N021 1/20 0.32
MEN1 O00255 1/20 0.32
KMT2A Q03164 1/20 0.32
ACHE P22303 1/20 0.31
FFAR3 O14843 1/20 0.31
LCK P06239 1/20 0.31
FYN P06241 1/20 0.31
FAAH O00519 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Trifluoroacetic Acid SCHEMBL474 1.00
Trifluoroacetic Acid SCHEMBL4598430 1.00
Trifluoroacetic Acid SCHEMBL30657022 1.00
Trifluoroacetic Acid SCHEMBL7814389 1.00 ALDH1A1 (0.44) ALDH1A1L3MBTL1TSHRTP53THRB
Trifluoroacetic Acid SCHEMBL25297651 0.95 ALDH1A1 (0.42) ALDH1A1L3MBTL1TSHRTP53THRB
Trifluoroacetic Acid SCHEMBL20571142 0.95
Trifluoroacetic Acid SCHEMBL901584 0.95
Trifluoroacetic Acid SCHEMBL21802705 0.95 ALDH1A1 (0.42) ALDH1A1L3MBTL1TSHRTP53THRB
Trifluoroacetic Acid SCHEMBL22712611 0.95
Trifluoroacetic Acid SCHEMBL20541014 0.95

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 235 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12516050-B2 Method for preparing isavuconazonium sulfate SHANGHAI DESANO BIO-PHARMACEUTICAL CO., LTD. (CN) 2026-01-06 US claimed
WO-2025111563-A1 MILK PEPTIDE COMPOSITIONS FOR PHARMACEUTICAL AND COSMECEUTICAL USE MATRUBIALS INC. (US) 2025-05-30 WO claimed
CN-116496358-A Preparation method of in vivo escape carrier cyclic peptide (CP-1) 南京盛肽医药科技有限公司 2023-07-28 CN claimed
US-20230075632-A1 METHOD FOR PREPARING ISAVUCONAZONIUM SULFATE SHANGHAI DESANO PHARMACEUTICALS CO., LTD. (CN) 2023-03-09 US claimed
EP-4083039-A1 METHOD FOR PREPARING ISAVUCONAZONIUM SULFATE Shanghai Desano Bio-Pharmaceutical Co., Ltd. (CN) 2022-11-02 EP claimed
EP-3817759-A1 A RECONSTITUTABLE TEVERELIX-TFA COMPOSITION Antev Limited (GB) 2021-05-12 EP claimed
CN-107406440-B BACE1 inhibitors 豪夫迈·罗氏有限公司 2021-05-07 CN claimed
US-20200308166-A1 BACE1 INHIBITORS HOFFMANN-LA ROCHE INC. 2020-10-01 US claimed
WO-2020007852-A1 A RECONSTITUTABLE TEVERELIX-TFA COMPOSITION ANTEV LIMITED (GB) 2020-01-09 WO claimed
US-10399969-B2 BACE1 inhibitors HOFFMANN-LA ROCHE INC. (US) 2019-09-03 US claimed
CN-103201280-B The compositions of suppression JAK approach and method 里格尔药品股份有限公司 2016-08-10 CN claimed
CN-103201280-A Compositions and methods for inhibition of the jak pathway RIGEL PHARMACEUTICALS INC 2013-07-10 CN claimed
EP-1827439-A2 NOVEL M3 MUSCARINIC ACETYLCHOLINE RECEPTOR ANTAGONISTS GLAXO GROUP LIMITED (GB) 2007-09-05 EP claimed
WO-2006055503-A2 NOVEL M3 MUSCARINIC ACETYLCHOLINE RECEPTOR ANTAGONISTS GLAXO GROUP LIMITED (GB) 2006-05-26 WO claimed
EP-1265867-B1 MALONIC ACID DERIVATES, PROCESSES FOR THEIR PREPARATION, THEIR USE AS INHIBITOR OF FACTOR XA ACTIVITY AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM SANOFI AVENTIS DEUTSCHLAND (DE) 2005-12-28 EP claimed
US-6794365-B2 INHIBITORS OF THE BLOOD CLOTTING ENZYME FACTOR XA; TREATING THROMBOEMBOLIC DISEASES; TRIFLUOROACETIC ACID SALT OF 2-(4-CARBAMIMIDOYL-BENZYL)-N-((1-CARBAMOYL-4-GUANIDINO-BUTYLCARBAMOYL) -CYCLOHEXYL-METHYL)-N',N'-DIMETHYL-MALONAMIDE AVENTIS PHARMA DEUTSCHLAND GMBH (DE) 2004-09-21 US claimed
EP-1265867-A1 NOVEL MALONIC ACID DERIVATES, PROCESSES FOR THEIR PREPARATION, THEIR USE AS INHIBITOR OF FACTOR XA ACTIVITY AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM Aventis Pharma Deutschland GmbH (DE) 2002-12-18 EP claimed
US-20020022596-A1 Novel malonic acid derivatives, processes for their preparation their use and pharmaceutical compositions containing them SANOFI-AVENTIS DEUTSCHLAND GMBH (DE) 2002-02-21 US claimed
WO-2001062735-A1 NOVEL MALONIC ACID DERIVATIVES, PROCESSES FOR THEIR PREPARATION, THEIR USE AS INHIBITOR OF FACTOR XA ACTIVITY AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AVENTIS PHARMA DEUTSCHLAND GMBH (DE) 2001-08-30 WO claimed
EP-1127884-A1 Novel malonic acid derivatives, processes for their preparation, their use as inhibitor of factor XA activity and pharmaceutical compositions containing them Aventis Pharma Deutschland GmbH (DE) 2001-08-29 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230075632-A1 METHOD FOR PREPARING ISAVUCONAZONIUM SULFATE STS, MPST, ARSA ALDH1A1 1511/4885L3MBTL1 4872/4885TSHR 3995/4885
US-10399969-B2 BACE1 inhibitors BACE1, BACE2, APP ALDH1A1 788/4885L3MBTL1 3525/4885TSHR 4825/4885
US-20020022596-A1 Novel malonic acid derivatives, processes for their preparation their use and pharmaceutical compositions containing them F12, ME1, F11 ALDH1A1 129/4885L3MBTL1 2204/4885TSHR 3149/4885
US-20200308166-A1 BACE1 INHIBITORS BACE1, BACE2, APP ALDH1A1 788/4885L3MBTL1 3525/4885TSHR 4825/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.