SCHEMBL1274615

SCHEMBL1274615

CC(C)(C)c1cc(CSc2cc(C(C)(C)C)c(O)c(C(C)(C)C)c2)cc(CSc2cc(C(C)(C)C)c(O)c(C(C)(C)C)c2)c1O

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSPA5 P11021 2/20 0.50
MAPT P10636 5/20 0.49
ALOX15 P16050 2/20 0.49
HPN P05981 1/20 0.49
SIRT5 Q9NXA8 1/20 0.49
ALDH1A1 P00352 8/20 0.45
TSHR P16473 3/20 0.45
GAA P10253 3/20 0.45
LMNA P02545 2/20 0.45
MAPK1 P28482 3/20 0.44
HIF1A Q16665 3/20 0.44
MEN1 O00255 3/20 0.44
KMT2A Q03164 3/20 0.44
CYP1A2 P05177 2/20 0.44
CYP3A4 P08684 2/20 0.44
BLM P54132 2/20 0.44
ATM Q13315 2/20 0.44
NPSR1 Q6W5P4 2/20 0.44
CYP2C9 P11712 2/20 0.44
CYP2C19 P33261 2/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1275766 0.86 HSPA5 (0.46) HSPA5MAPTALOX15HPNSIRT5
SCHEMBL1275820 0.85 HSPA5 (0.45) HSPA5MAPTALOX15HPNSIRT5
SCHEMBL1275488 0.84 HSPA5 (0.44) HSPA5MAPTALOX15HPNSIRT5
SCHEMBL8496233 0.83 MAPT (0.55) HSPA5MAPTALOX15HPNSIRT5
SCHEMBL1275493 0.82 APP (0.47) HSPA5MAPTALDH1A1CA2CA1
SCHEMBL14000580 0.79 HSPA5 (0.56) HSPA5MAPTALOX15HPNSIRT5
SCHEMBL1274870 0.78 HSPA5 (0.54) HSPA5MAPTALOX15HPNSIRT5
SCHEMBL8698399 0.77 PTGS1 (0.49) HSPA5MAPTALOX15HPNSIRT5
SCHEMBL1275754 0.77 HSPA5 (0.53) HSPA5MAPTALOX15HPNSIRT5
SCHEMBL6054593 0.76 PTGS1 (0.50) MAPTALOX15HPNSIRT5ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1249845-B1 Stabilized medium and high voltage cable insulation composition BASF SE (DE) 2012-07-11 EP disclosed
EP-1848768-B1 CROSS-LINKED POLYETHYLENE HAVING EXCELLENT INHIBITION OF SWEAT-OUT AND INSULATION PROPERTIES LG CHEMICAL LTD (KR) 2011-02-09 EP disclosed
US-7452933-B2 Cross-linked polyethylene having excellent inhibition of sweat-out and insulation properties LG CHEM, LTD. (KR) 2008-11-18 US disclosed
EP-1848768-A4 CROSS-LINKED POLYETHYLENE HAVING EXCELLENT INHIBITION OF SWEAT-OUT AND INSULATION PROPERTIES LG CHEMICAL LTD (KR) 2008-06-11 EP disclosed
EP-1848768-A1 CROSS-LINKED POLYETHYLENE HAVING EXCELLENT INHIBITION OF SWEAT-OUT AND INSULATION PROPERTIES LG Chem, Ltd. (KR) 2007-10-31 EP disclosed
WO-2007097511-A1 CROSS-LINKED POLYETHYLENE HAVING EXCELLENT INHIBITION OF SWEAT-OUT AND INSULATION PROPERTIES LG CHEM, LTD. (KR) 2007-08-30 WO disclosed
US-20070203278-A1 CROSS-LINKED POLYETHYLENE HAVING EXCELLENT INHIBITION OF SWEAT-OUT AND INSULATION PROPERTIES LG CHEM, LTD. (KR) 2007-08-30 US disclosed
US-7056967-B2 Stabilized medium and high voltage cable insulation composition CIBA SPECIALTY CHEMICALS CORPORATION (US) 2006-06-06 US disclosed
US-20020198344-A1 Stabilized medium and high voltage cable insulation composition CIBA SPECIALTY CHEMICALS CORP. 2002-12-26 US disclosed
EP-1249845-A2 Stabilized medium and high voltage cable insulation composition Ciba SC Holding AG (CH) 2002-10-16 EP disclosed
EP-0165209-B1 O,P-BIFUNCTIONALISED, O'-SUBSTITUTED PHENOLS CIBA-GEIGY AG (CH) 1989-07-19 EP disclosed
US-4759862-A O,p-bifunctionalized o'-substituted phenols CIBA-GEIGY CORPORATION (US) 1988-07-26 US disclosed
EP-0165209-A2 o,p-Bifunctionalised, o'-substituted phenols CIBA-GEIGY AG (CH) 1985-12-18 EP disclosed