SCHEMBL1275488

SCHEMBL1275488

CC(C)(C)c1cc(CSc2ccc(Cl)cc2)cc(CSc2ccc(Cl)cc2)c1O

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSPA5 P11021 2/20 0.44
MEN1 O00255 5/20 0.42
KMT2A Q03164 5/20 0.42
ALDH1A1 P00352 4/20 0.42
RAB9A P51151 4/20 0.42
NPC1 O15118 3/20 0.42
MAPT P10636 4/20 0.39
LMNA P02545 4/20 0.39
HPGD P15428 2/20 0.39
MAOA P21397 2/20 0.39
MAOB P27338 2/20 0.39
GAA P10253 2/20 0.38
KDM4E B2RXH2 1/20 0.38
TDP1 Q9NUW8 1/20 0.38
DAO P14920 2/20 0.37
SMN1; SMN2 Q16637 4/20 0.37
L3MBTL1 Q9Y468 1/20 0.37
TSHR P16473 1/20 0.36
SOD1 P00441 1/20 0.36
NPSR1 Q6W5P4 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1275820 0.87 HSPA5 (0.45) HSPA5MEN1KMT2AALDH1A1RAB9A
SCHEMBL1275766 0.86 HSPA5 (0.46) HSPA5MEN1KMT2AALDH1A1MAPT
SCHEMBL1274615 0.84 HSPA5 (0.50) HSPA5MEN1KMT2AALDH1A1MAPT
SCHEMBL1275493 0.84 APP (0.47) HSPA5ALDH1A1MAPTMAOAMAOB
SCHEMBL14000580 0.79 HSPA5 (0.56) HSPA5MEN1KMT2AALDH1A1MAPT
SCHEMBL23766413 0.72 L3MBTL1 (0.43) HSPA5MEN1KMT2AALDH1A1NPC1
SCHEMBL1274870 0.72 HSPA5 (0.54) HSPA5MEN1KMT2AALDH1A1MAPT
SCHEMBL1275754 0.71 HSPA5 (0.53) HSPA5MEN1KMT2AALDH1A1MAPT
SCHEMBL8496233 0.71 MAPT (0.55) HSPA5MEN1KMT2AALDH1A1MAPT
SCHEMBL1275152 0.70 HSPA5 (0.56) HSPA5MEN1KMT2AALDH1A1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1249845-B1 Stabilized medium and high voltage cable insulation composition BASF SE (DE) 2012-07-11 EP disclosed
EP-1848768-B1 CROSS-LINKED POLYETHYLENE HAVING EXCELLENT INHIBITION OF SWEAT-OUT AND INSULATION PROPERTIES LG CHEMICAL LTD (KR) 2011-02-09 EP disclosed
US-7452933-B2 Cross-linked polyethylene having excellent inhibition of sweat-out and insulation properties LG CHEM, LTD. (KR) 2008-11-18 US disclosed
EP-1848768-A4 CROSS-LINKED POLYETHYLENE HAVING EXCELLENT INHIBITION OF SWEAT-OUT AND INSULATION PROPERTIES LG CHEMICAL LTD (KR) 2008-06-11 EP disclosed
EP-1848768-A1 CROSS-LINKED POLYETHYLENE HAVING EXCELLENT INHIBITION OF SWEAT-OUT AND INSULATION PROPERTIES LG Chem, Ltd. (KR) 2007-10-31 EP disclosed
WO-2007097511-A1 CROSS-LINKED POLYETHYLENE HAVING EXCELLENT INHIBITION OF SWEAT-OUT AND INSULATION PROPERTIES LG CHEM, LTD. (KR) 2007-08-30 WO disclosed
US-20070203278-A1 CROSS-LINKED POLYETHYLENE HAVING EXCELLENT INHIBITION OF SWEAT-OUT AND INSULATION PROPERTIES LG CHEM, LTD. (KR) 2007-08-30 US disclosed
US-7056967-B2 Stabilized medium and high voltage cable insulation composition CIBA SPECIALTY CHEMICALS CORPORATION (US) 2006-06-06 US disclosed
US-20020198344-A1 Stabilized medium and high voltage cable insulation composition CIBA SPECIALTY CHEMICALS CORP. 2002-12-26 US disclosed
EP-1249845-A2 Stabilized medium and high voltage cable insulation composition Ciba SC Holding AG (CH) 2002-10-16 EP disclosed
EP-0165209-B1 O,P-BIFUNCTIONALISED, O'-SUBSTITUTED PHENOLS CIBA-GEIGY AG (CH) 1989-07-19 EP disclosed
US-4759862-A O,p-bifunctionalized o'-substituted phenols CIBA-GEIGY CORPORATION (US) 1988-07-26 US disclosed
EP-0165209-A2 o,p-Bifunctionalised, o'-substituted phenols CIBA-GEIGY AG (CH) 1985-12-18 EP disclosed