Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 2/20 | 0.49 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 5/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.49 |
| ▸ | HPN | P05981 | 1/20 | 0.49 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.48 |
| ▸ | CA2 | P00918 | 2/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | TYR | P14679 | 1/20 | 0.48 |
| ▸ | DAO | P14920 | 1/20 | 0.48 |
| ▸ | F2R | P25116 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | HSPA5 | P11021 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 4/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8496233 | 0.93 | MAPT (0.55) | MAPTALOX15HPNSIRT5ALDH1A1 | |
| SCHEMBL6054593 | 0.86 | PTGS1 (0.50) | PTGS1PTGS2MAPTALOX15HPN | |
| SCHEMBL9417705 | 0.82 | ALDH1A1 (0.45) | MAPTALOX15HPNSIRT5ALDH1A1 | |
| SCHEMBL9417710 | 0.82 | MAOB (0.50) | MAPTALOX15HPNSIRT5ALDH1A1 | |
| SCHEMBL1275820 | 0.79 | HSPA5 (0.45) | PTGS1PTGS2MAPTALOX15HPN | |
| SCHEMBL6054565 | 0.79 | EPHX2 (0.44) | PTGS1PTGS2MAPTALOX15HPN | |
| SCHEMBL6054514 | 0.79 | ALDH1A1 (0.41) | PTGS1PTGS2MAPTALOX15HPN | |
| SCHEMBL9362051 | 0.78 | LMNA (0.43) | PTGS1PTGS2MAPTALOX15HPN | |
| SCHEMBL1274615 | 0.77 | HSPA5 (0.50) | MAPTALOX15HPNSIRT5ALDH1A1 | |
| SCHEMBL8767800 | 0.77 | PPARA (0.52) | MAPTMEN1KMT2ACYP2C19CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0482071-B1 | NEW ANTIVIRAL AGENTS | BIODOR US HOLDING CORP (US) | 1998-01-07 | — | — | EP | claimed |