Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.31 |
| ▸ | GLA | P06280 | 1/20 | 0.31 |
| ▸ | BLM | P54132 | 1/20 | 0.31 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13970127 | 0.88 | KDM4E (0.33) | LMNARAB9ASMN1; SMN2ADORA2BGLA | |
| SCHEMBL12748995 | 0.88 | KDM4E (0.33) | LMNARAB9ASMN1; SMN2ADORA2BGLA | |
| SCHEMBL12749037 | 0.81 | — | — | |
| SCHEMBL13970128 | 0.75 | LMNA (0.31) | LMNARAB9ASMN1; SMN2ADORA2BGLA | |
| SCHEMBL1902451 | 0.69 | TYMP (0.42) | LMNASMN1; SMN2BLM | |
| SCHEMBL6555940 | 0.69 | TYMP (0.42) | LMNASMN1; SMN2BLM | |
| SCHEMBL12748530 | 0.69 | TYMP (0.42) | LMNASMN1; SMN2BLM | |
| SCHEMBL14068444 | 0.68 | CHRNE (0.31) | — | |
| SCHEMBL13970113 | 0.67 | — | — | |
| SCHEMBL13083849 | 0.64 | ADORA2B (0.33) | LMNARAB9ASMN1; SMN2ADORA2BGLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7928210-B2 | Nucleoside based proliferation imaging markers | SIEMENS MEDICAL SOLUTIONS USA, INC. (US) | 2011-04-19 | — | — | US | disclosed |
| WO-2008109080-A2 | NUCLEOSIDE BASED PROLIFERATION IMAGING MARKERS | SIEMENS MEDICAL SOLUTIONS USA, INC. (US) | 2008-09-12 | — | — | WO | disclosed |