Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 8/20 | 0.51 |
| ▸ | LMNA | P02545 | 4/20 | 0.44 |
| ▸ | NPC1 | O15118 | 3/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | NFKB1 | P19838 | 3/20 | 0.43 |
| ▸ | NFKB2 | Q00653 | 3/20 | 0.43 |
| ▸ | RELA | Q04206 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.42 |
| ▸ | ACR | P10323 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.40 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.40 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12749046 | 0.97 | MAPT (0.48) | MAPTLMNANPC1CYP1A2CYP2C9 | |
| SCHEMBL8925519 | 0.83 | LMNA (0.48) | MAPTLMNANPC1CYP1A2CYP2C9 | |
| SCHEMBL9304783 | 0.81 | LMNA (0.47) | MAPTLMNANPC1CYP1A2CYP2C9 | |
| SCHEMBL10613722 | 0.80 | NPC1 (0.63) | MAPTLMNANPC1CYP1A2CYP2C9 | |
| SCHEMBL10611919 | 0.80 | NPC1 (0.63) | MAPTLMNANPC1CYP1A2CYP2C9 | |
| SCHEMBL10610897 | 0.80 | NPC1 (0.63) | MAPTLMNANPC1CYP1A2CYP2C9 | |
| SCHEMBL8990073 | 0.80 | NPC1 (0.63) | MAPTLMNANPC1CYP1A2CYP2C9 | |
| SCHEMBL10613750 | 0.80 | MAPT (0.57) | MAPTLMNANPC1CYP1A2CYP2C9 | |
| SCHEMBL11037678 | 0.80 | NPC1 (0.63) | MAPTLMNANPC1CYP1A2CYP2C9 | |
| SCHEMBL10721803 | 0.80 | NPC1 (0.63) | MAPTLMNANPC1CYP1A2CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7914485-B2 | Medical device employing liquid crystal block copolymers and method of making the same | BOSTON SCIENTIFIC SCIMED, INC. (US) | 2011-03-29 | — | — | US | disclosed |
| US-20100016941-A1 | MEDICAL DEVICE EMPLOYING LIQUID CRYSTAL BLOCK COPOLYMERS AND METHOD OF MAKING THE SAME | BOSTON SCIENTIFIC SCIMED, INC. (US) | 2010-01-21 | — | — | US | disclosed |
| US-7582078-B2 | Medical device employing liquid crystal block copolymers and method of making the same | BOSTON SCIENTIFIC SCIMED, INC. (US) | 2009-09-01 | — | — | US | disclosed |
| US-20070191814-A1 | Medical device employing liquid crystal block copolymers and method of making the same | BOSTON SCIENTIFIC SCIMED, INC. (US) | 2007-08-16 | — | — | US | disclosed |