Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 5/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | NPC1 | O15118 | 3/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 5/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.46 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.46 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.46 |
| ▸ | RELA | Q04206 | 1/20 | 0.46 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.44 |
| ▸ | ACR | P10323 | 2/20 | 0.44 |
| ▸ | GFER | P55789 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12749048 | 0.83 | MAPT (0.51) | LMNACYP1A2CYP2C9CYP2C19SMN1; SMN2 | |
| SCHEMBL8927099 | 0.83 | TSHR (0.55) | TSHRALDH1A1 | |
| SCHEMBL12749046 | 0.81 | MAPT (0.48) | LMNACYP1A2CYP2C9CYP2C19SMN1; SMN2 | |
| SCHEMBL13205233 | 0.80 | LMNA (0.50) | LMNACYP1A2CYP2C9CYP2C19SMN1; SMN2 | |
| SCHEMBL14566203 | 0.79 | LMNA (0.67) | LMNACYP1A2CYP2C9CYP2C19SMN1; SMN2 | |
| SCHEMBL3462397 | 0.79 | GAA (0.55) | LMNASMN1; SMN2MAPTKDM4EALDH1A1 | |
| SCHEMBL11911717 | 0.77 | LMNA (0.47) | LMNACYP1A2CYP2C9CYP2C19SMN1; SMN2 | |
| SCHEMBL12744489 | 0.77 | MAPT (0.56) | LMNACYP1A2CYP2C9CYP2C19SMN1; SMN2 | |
| SCHEMBL23771262 | 0.76 | LMNA (0.72) | LMNACYP1A2CYP2C9CYP2C19SMN1; SMN2 | |
| SCHEMBL18722269 | 0.76 | NPC1 (0.58) | LMNACYP1A2CYP2C9CYP2C19SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5605649-A | LOW VISCOSITY, THERMOCHROMIC PROPERTIES | CONSORTIUM FUR ELEKTROCHEMISCHE INDUSTRIE GMBH (DE) | 1997-02-25 | — | — | US | disclosed |