Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 2/20 | 0.42 |
| ▸ | MPL | P40238 | 2/20 | 0.42 |
| ▸ | CYP11B2 | P19099 | 7/20 | 0.38 |
| ▸ | CYP11B1 | P15538 | 6/20 | 0.38 |
| ▸ | APP | P05067 | 1/20 | 0.38 |
| ▸ | ALOX5AP | P20292 | 2/20 | 0.38 |
| ▸ | FEN1 | P39748 | 2/20 | 0.38 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.37 |
| ▸ | PDE2A | O00408 | 3/20 | 0.37 |
| ▸ | GPR3 | P46089 | 1/20 | 0.34 |
| ▸ | CDC14B | O60729 | 1/20 | 0.34 |
| ▸ | CDC14A | Q9UNH5 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27705144 | 0.85 | ALOX5AP (0.31) | IDO1MPLAPPALOX5APFEN1 | |
| SCHEMBL17134063 | 0.77 | IDO1 (0.36) | IDO1PDE2A | |
| SCHEMBL1275706 | 0.73 | MPL (0.40) | IDO1MPLCYP11B2CYP11B1APP | |
| SCHEMBL9736244 | 0.71 | IDO1 (0.41) | IDO1MPLCYP11B2CYP11B1APP | |
| SCHEMBL6039958 | 0.68 | MPL (0.47) | IDO1MPLCYP11B2CYP11B1APP | |
| SCHEMBL30568357 | 0.68 | MPL (0.55) | IDO1MPLPDE2AGPR3 | |
| SCHEMBL18361131 | 0.68 | MPL (0.55) | IDO1MPLPDE2AGPR3 | |
| SCHEMBL4395172 | 0.68 | GPR3 (0.33) | GPR3 | |
| SCHEMBL12887901 | 0.68 | GPR3 (0.48) | MPLGPR3 | |
| SCHEMBL20526087 | 0.67 | CES2 (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2461685-A2 | MIXTURES OF MESOIONIC PESTICIDES | E. I. du Pont de Nemours and Company (US) | 2012-06-13 | — | — | EP | disclosed |
| WO-2011017351-A2 | MIXTURES OF MESOIONIC PESTICIDES | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2011-02-10 | — | — | WO | disclosed |