SCHEMBL1275772

SCHEMBL1275772

CC(C)(C)c1cc(CSCC(=O)OCc2ccccc2)cc(CSCC(=O)OCc2ccccc2)c1O

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CDC25B P30305 1/20 0.41
L3MBTL1 Q9Y468 3/20 0.40
ALDH1A1 P00352 2/20 0.40
MAPK1 P28482 1/20 0.40
MEN1 O00255 1/20 0.39
GAA P10253 1/20 0.39
KMT2A Q03164 1/20 0.39
HSPA5 P11021 1/20 0.38
TSHR P16473 1/20 0.37
PPARG P37231 1/20 0.36
PPARA Q07869 1/20 0.36
CYP1A2 P05177 2/20 0.36
CCNB2 O95067 1/20 0.36
CCNE2 O96020 1/20 0.36
CDK1 P06493 1/20 0.36
CDK4 P11802 1/20 0.36
CCNB1 P14635 1/20 0.36
CCND1 P24385 1/20 0.36
CCNE1 P24864 1/20 0.36
CDK2 P24941 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1275457 0.85 LMNA (0.40) L3MBTL1MEN1GAAKMT2AHSPA5
SCHEMBL1275477 0.82 HSPA5 (0.47) ALDH1A1MAPK1MEN1GAAKMT2A
SCHEMBL1275788 0.81 HSPA5 (0.44) ALDH1A1MAPK1MEN1GAAKMT2A
SCHEMBL4633458 0.81 HSPA5 (0.46) ALDH1A1MAPK1MEN1GAAKMT2A
SCHEMBL1274613 0.81 HSPA5 (0.40) ALDH1A1MAPK1MEN1GAAKMT2A
SCHEMBL1275167 0.80 HSPA5 (0.39) ALDH1A1MAPK1MEN1GAAKMT2A
SCHEMBL1274866 0.80 HSPA5 (0.42) L3MBTL1ALDH1A1GAAKMT2AHSPA5
SCHEMBL1275785 0.80 ALDH1A1 (0.41) ALDH1A1MAPK1MEN1GAAKMT2A
SCHEMBL1275783 0.80 ALDH1A1 (0.41) ALDH1A1MAPK1MEN1GAAKMT2A
SCHEMBL1275191 0.79 HSPA5 (0.46) ALDH1A1MAPK1MEN1GAAKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1848768-B1 CROSS-LINKED POLYETHYLENE HAVING EXCELLENT INHIBITION OF SWEAT-OUT AND INSULATION PROPERTIES LG CHEMICAL LTD (KR) 2011-02-09 EP disclosed
US-7452933-B2 Cross-linked polyethylene having excellent inhibition of sweat-out and insulation properties LG CHEM, LTD. (KR) 2008-11-18 US disclosed
EP-1848768-A4 CROSS-LINKED POLYETHYLENE HAVING EXCELLENT INHIBITION OF SWEAT-OUT AND INSULATION PROPERTIES LG CHEMICAL LTD (KR) 2008-06-11 EP disclosed
EP-1848768-A1 CROSS-LINKED POLYETHYLENE HAVING EXCELLENT INHIBITION OF SWEAT-OUT AND INSULATION PROPERTIES LG Chem, Ltd. (KR) 2007-10-31 EP disclosed
WO-2007097511-A1 CROSS-LINKED POLYETHYLENE HAVING EXCELLENT INHIBITION OF SWEAT-OUT AND INSULATION PROPERTIES LG CHEM, LTD. (KR) 2007-08-30 WO disclosed
US-20070203278-A1 CROSS-LINKED POLYETHYLENE HAVING EXCELLENT INHIBITION OF SWEAT-OUT AND INSULATION PROPERTIES LG CHEM, LTD. (KR) 2007-08-30 US disclosed