Sugi Predict

Sugi Predict / Compounds / SCHEMBL1275792

SCHEMBL1275792

SCHEMBL1275792

CCCCCCCCN/C(C)=C(/CC)C(=O)O

nearest known ligand 0.53

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
▸ EPHX1 P07099 10/20 0.53
▸ CASP2 P42575 1/20 0.48
▸ THRB P10828 1/20 0.47
▸ FNTA P49354 1/20 0.47
▸ FNTB P49356 1/20 0.47
▸ PGGT1B P53609 1/20 0.47
▸ FAAH O00519 1/20 0.46
▸ NAAA Q02083 2/20 0.46
▸ ZDHHC20 Q5W0Z9 1/20 0.46
▸ ZDHHC2 Q9UIJ5 1/20 0.46
▸ PLA2G2A P14555 1/20 0.45
▸ PRCP P42785 1/20 0.44
▸ KDM4E B2RXH2 1/20 0.43
▸ MAPK1 P28482 1/20 0.43
▸ HIF1A Q16665 1/20 0.43
▸ ALDH1A1 P00352 1/20 0.42
▸ HTT P42858 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1275796 1.00 EPHX1 (0.53) EPHX1CASP2THRBFNTAFNTB
SCHEMBL15567984 0.92 EPHX1 (0.45) EPHX1THRBFNTAFNTBPGGT1B
SCHEMBL2128891 0.92 EPHX1 (0.45) EPHX1THRBFNTAFNTBPGGT1B
SCHEMBL9017540 0.88 EPHX1 (0.42) EPHX1CASP2THRBFNTAFNTB
SCHEMBL9017544 0.88 EPHX1 (0.42) EPHX1CASP2THRBFNTAFNTB
SCHEMBL3285612 0.81 EPHX1 (0.57) EPHX1CASP2THRBFNTAFNTB
SCHEMBL17845063 0.81 EPHX1 (0.57) EPHX1CASP2THRBFNTAFNTB
SCHEMBL3284591 0.81 EPHX1 (0.57) EPHX1CASP2THRBFNTAFNTB
SCHEMBL3277705 0.81 EPHX1 (0.57) EPHX1CASP2THRBFNTAFNTB
SCHEMBL17845061 0.81 EPHX1 (0.57) EPHX1CASP2THRBFNTAFNTB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 36 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1353642-B1 PHOTOPROTECTIVE COMPOSITIONS COMPRISING AN AMPHIPHILIC COPOYLMER COMPRISING 2-ACRYLAMIDO-2-PROPANESULFONIC AND (METH)ACRYLATES OREAL (FR) 2008-05-07 — — EP claimed
EP-1093798-B1 Emulsions without emulsifiers containing at least one insoluble organic UV-filter OREAL (FR) 2005-08-31 — — EP claimed
EP-1093796-B1 Emulsions containing one or more insoluble organic UV-filter and an associative polymer OREAL (FR) 2003-02-05 — — EP claimed
EP-1093799-B1 Water-in-Oil emulsions containing at least one insoluble organic UV filter and a non-filtrating organomodified silicone OREAL (FR) 2002-08-07 — — EP claimed
EP-1093797-B1 Process for the photostabilisation of sunscreens derived from dibenzoylmethane by an insoluble organic filter OREAL (FR) 2002-02-20 — — EP claimed
EP-0840595-B1 SUNSCREEN COMPOSITIONS CIBA SC HOLDING AG (CH) 2000-10-04 — — EP claimed
US-5980872-A Sunscreen compositions CIBA SPECIALTY CHEMICALS CORPORATION (US) 1999-11-09 — — US claimed
EP-0840595-A1 SUNSCREEN COMPOSITIONS Ciba SC Holding AG (CH) 1998-05-13 — — EP claimed
WO-1997003643-A1 SUNSCREEN COMPOSITIONS CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 1997-02-06 — — WO claimed
US-20210346249-A1 COMPOSITION COMPRISING A UV-SCREENING AGENT, AN ANIONIC CROSSLINKED HYDROPHILIC POLYMER, A SURFACTANT HAVING AN HLB LESS THAN OR EQUAL TO 5 AND A SILICONE COPOLYMER L'OREAL (FR) 2021-11-11 — — US disclosed
US-20200030200-A1 COMPOSITION COMPRISING A UV-SCREENING AGENT, AN ANIONIC CROSSLINKED HYDROPHILIC POLYMER, A SURFACTANT HAVING AN HLB LESS THAN OR EQUAL TO 5 AND A SILICONE COPOLYMER L'OREAL (FR) 2020-01-30 — — US disclosed
EP-3307233-B1 COMPOSITION COMPRISING A UV-SCREENING AGENT, AN ANIONIC CROSSLINKED HYDROPHILIC POLYMER, A SURFACTANT HAVING AN HLB LESS THAN OR EQUAL TO 5 AND A SILICONE COPOLYMER OREAL (FR) 2019-11-06 — — EP disclosed
EP-3307233-A1 COMPOSITION COMPRISING A UV-SCREENING AGENT, AN ANIONIC CROSSLINKED HYDROPHILIC POLYMER, A SURFACTANT HAVING AN HLB LESS THAN OR EQUAL TO 5 AND A SILICONE COPOLYMER L'Oréal (FR) 2018-04-18 — — EP disclosed
CN-103443207-B composite pigment and preparation method thereof 莱雅公司 2018-01-30 — — CN disclosed
EP-0840595-B1 SUNSCREEN COMPOSITIONS CIBA SC HOLDING AG (CH) 2000-10-04 — — EP disclosed
EP-0746305-B1 SUNSCREEN COMPOSITIONS CIBA SC HOLDING AG (CH) 2000-01-05 — — EP disclosed
US-5980872-A Sunscreen compositions CIBA SPECIALTY CHEMICALS CORPORATION (US) 1999-11-09 — — US disclosed
US-5869030-A OXALANILIDE, TRIAZINE, TRIAZOLE, VINYL GROUP-CONTAINING AMIDE OR CINNAMIC ACID AMIDE CIBA SPECIALTY CHEMICALS CORPORATION (US) 1999-02-09 — — US disclosed
EP-0840595-A1 SUNSCREEN COMPOSITIONS Ciba SC Holding AG (CH) 1998-05-13 — — EP disclosed
WO-1997003643-A1 SUNSCREEN COMPOSITIONS CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 1997-02-06 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200030200-A1 COMPOSITION COMPRISING A UV-SCREENING AGENT, AN ANIONIC CROSSLINKED HYDROPHILIC POLYMER, A SURFACTANT HAVING AN HLB LESS THAN OR EQUAL TO 5 AND A SILICONE COPOLYMER ERCC5, CUTA, PLIN5 EPHX1 633/4885CASP2 3490/4885THRB 1865/4885
US-20210346249-A1 COMPOSITION COMPRISING A UV-SCREENING AGENT, AN ANIONIC CROSSLINKED HYDROPHILIC POLYMER, A SURFACTANT HAVING AN HLB LESS THAN OR EQUAL TO 5 AND A SILICONE COPOLYMER ERCC5, CUTA, PLIN5 EPHX1 633/4885CASP2 3490/4885THRB 1865/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.