Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | APEX1 | P27695 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12373196 | 1.00 | TSHR (0.44) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL27454755 | 0.97 | TSHR (0.46) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL9764030 | 0.97 | TSHR (0.46) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL9179072 | 0.97 | TSHR (0.46) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL10115291 | 0.97 | TSHR (0.46) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL2368062 | 0.96 | TSHR (0.47) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL17069794 | 0.93 | TSHR (0.50) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL11919878 | 0.93 | TSHR (0.50) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL19239961 | 0.93 | TSHR (0.50) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL15355901 | 0.91 | TSHR (0.50) | TSHRTHRBPOLBAPEX1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8827447-B2 | Mono ethylenically unsaturated polymerizable group containing polycarbosiloxane monomers | BAUSCH & LOMB INCORPORATED (US) | 2014-09-09 | — | — | US | disclosed |
| US-20130197125-A1 | MONO ETHYLENICALLY UNSATURATED POLYMERIZABLE GROUP CONTAINING POLYCARBOSILOXANE MONOMERS | BAUSCH & LOMB INCORPORATED (US) | 2013-08-01 | — | — | US | disclosed |
| US-8420711-B2 | Mono ethylenically unsaturated polymerizable group containing polycarbosiloxane monomers | BAUSCH & LOMB INCORPORATED (US) | 2013-04-16 | — | — | US | disclosed |
| US-7915323-B2 | Mono ethylenically unsaturated polycarbosiloxane monomers | BAUSCH & LAMB INCORPORATED (US) | 2011-03-29 | — | — | US | disclosed |
| US-20110009519-A1 | MONO ETHYLENICALLY UNSATURATED POLYMERIZABLE GROUP CONTAINING POLYCARBOSILOXANE MONOMERS | SOLTA MEDICAL, INC. | 2011-01-13 | — | — | US | disclosed |