SCHEMBL2368062

SCHEMBL2368062

C=C(C)C(=O)OCCC[Si](C)(C)O[Si](C)(C)O[Si](C)(C)C

nearest known ligand 0.47

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.47
THRB P10828 1/20 0.41
POLB P06746 1/20 0.38
APEX1 P27695 1/20 0.38
HTT P42858 1/20 0.38
TDP1 Q9NUW8 1/20 0.38
ALDH1A1 P00352 2/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27454755 0.98 TSHR (0.46) TSHRTHRBPOLBAPEX1HTT
SCHEMBL9179072 0.98 TSHR (0.46) TSHRTHRBPOLBAPEX1HTT
SCHEMBL9764030 0.98 TSHR (0.46) TSHRTHRBPOLBAPEX1HTT
SCHEMBL10115291 0.98 TSHR (0.46) TSHRTHRBPOLBAPEX1HTT
SCHEMBL12373196 0.96 TSHR (0.44) TSHRTHRBPOLBAPEX1HTT
SCHEMBL12759270 0.96 TSHR (0.44) TSHRTHRBPOLBAPEX1HTT
SCHEMBL2367838 0.95 TSHR (0.51) TSHRTHRBPOLBAPEX1HTT
SCHEMBL17069794 0.94 TSHR (0.50) TSHRTHRBPOLBAPEX1HTT
SCHEMBL11919878 0.94 TSHR (0.50) TSHRTHRBPOLBAPEX1HTT
SCHEMBL19239961 0.94 TSHR (0.50) TSHRTHRBPOLBAPEX1HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4988788-A Room temperature-curable coating composition SHIN-ETSU CHEMICAL CO., LTD. (JP) 1991-01-29 US claimed
US-20240068158-A1 SILICONE - (METH)ACRYLATE COPOLYMER FORMULATION AND PROCESSES FOR PREPARATION AND USE THEREOF DOW SILICONES CORP (US) 2024-02-29 US disclosed
US-11781040-B2 Adhesive film and optical member comprising same SAMSUNG SDI CO., LTD. (KR) 2023-10-10 US disclosed
US-20170240677-A1 FILM-FORMING COMPOSITION AND COSMETIC SHIN-ETSU CHEMICAL CO., LTD. (JP) 2017-08-24 US disclosed
US-20170197995-A1 PROCESS FOR PREPARATION OF 3-METHACRYLOXYPROPYLDIMETHYLCHLOROSILANE IN CONTINUOUS FLOW REACTOR GEO SPECIALTY CHEMICALS UK LIMITED (GB) 2017-07-13 US disclosed
US-9522998-B2 Resin mold material composition for imprinting DAIKIN INDUSTRIES, LTD. (JP) 2016-12-20 US disclosed
US-9188702-B2 Silicone hydrogels having improved curing speed and other properties JOHNSON & JOHNSON VISION CARE, INC. (US) 2015-11-17 US disclosed
US-9108367-B2 Method for manufacturing contact lenses and contact lenses manufactured therefrom BENQ MATERIALS CORPORATION (TW) 2015-08-18 US disclosed
US-8980404-B2 Composition for imprints, pattern and patterning method FUJIFILM CORPORATION (JP) 2015-03-17 US disclosed
US-20150064909-A1 RESIN MOLD MATERIAL COMPOSITION FOR IMPRINTING DAIKIN INDUSTRIES, LTD. (JP) 2015-03-05 US disclosed
US-20130085205-A1 SILICONE HYDROGELS HAVING IMPROVED CURING SPEED AND OTHER PROPERTIES JOHNSON & JOHNSON VISION CARE, INC. 2013-04-04 US disclosed
US-8329067-B2 Method of producing color filter and color filter DAI NIPPON PRINTING CO., LTD. (JP) 2012-12-11 US disclosed
US-8288496-B2 Contact lens and its manufacturing method NIPPON CONTACT LENS INC. (JP) 2012-10-16 US disclosed
US-20110237701-A1 CONTACT LENS AND ITS MANUFACTURING METHOD NIPPON CONTACT LENS INC. (JP) 2011-09-29 US disclosed
EP-2369370-A2 Contact lens and its manufacturing method Nippon Contact Lens Inc. (JP) 2011-09-28 EP disclosed
US-20110183127-A1 COMPOSITION FOR IMPRINTS, PATTERN AND PATTERNING METHOD FUJIFILM CORPORATION (JP) 2011-07-28 US disclosed
US-7709170-B2 Latent electrostatic image bearing member, and process cartridge, image forming apparatus and image forming method RICOH COMPANY, LTD. (JP) 2010-05-04 US disclosed
US-20090114888-A1 METHOD OF PRODUCING COLOR FILTER AND COLOR FILTER DAI NIPPON PRINTING CO., LTD. (JP) 2009-05-07 US disclosed
US-20080004383-A1 ACRYLOYL MATERIALS FOR MOLDED PLASTICS TORAY INDUSTRIES, INC. (JP) 2008-01-03 US disclosed
US-4743667-A ACRYLATED SILOXXANES, OXYGEN PERMEABLE NIPPON CONTACT LENS, INC. (JP) 1988-05-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170240677-A1 FILM-FORMING COMPOSITION AND COSMETIC RAD51, FEM1B, H1-0 TSHR 1060/4885THRB 1066/4885POLB 1890/4885
US-20170197995-A1 PROCESS FOR PREPARATION OF 3-METHACRYLOXYPROPYLDIMETHYLCHLOROSILANE IN CONTINUOUS FLOW REACTOR SAMM50, MPST, AS3MT TSHR 4219/4885THRB 4639/4885POLB 715/4885
US-20080004383-A1 ACRYLOYL MATERIALS FOR MOLDED PLASTICS ACR, HAAO, PORCN TSHR 4861/4885THRB 4816/4885POLB 4470/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.