⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10030119 | 0.98 | CES2 (0.31) | — | |
| SCHEMBL13219007 | 0.92 | CES1 (0.38) | — | |
| SCHEMBL12972539 | 0.87 | CES1 (0.37) | — | |
| SCHEMBL12775038 | 0.85 | CES1 (0.31) | — | |
| SCHEMBL15469253 | 0.82 | CES2 (0.31) | — | |
| SCHEMBL20942828 | 0.82 | — | — | |
| SCHEMBL10329839 | 0.80 | TSHR (0.45) | — | |
| SCHEMBL17211885 | 0.77 | — | — | |
| SCHEMBL8850235 | 0.77 | CES2 (0.30) | — | |
| SCHEMBL13559944 | 0.77 | TSHR (0.53) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8827447-B2 | Mono ethylenically unsaturated polymerizable group containing polycarbosiloxane monomers | BAUSCH & LOMB INCORPORATED (US) | 2014-09-09 | — | — | US | disclosed |
| US-20130289294-A1 | ETHYLENICALLY UNSATURATED POLYMERIZABLE GROUPS COMPRISING POLYCARBOSILOXANE MONOMERS | BAUSCH HEALTH AMERICAS, INC. | 2013-10-31 | — | — | US | disclosed |
| US-20130197125-A1 | MONO ETHYLENICALLY UNSATURATED POLYMERIZABLE GROUP CONTAINING POLYCARBOSILOXANE MONOMERS | BAUSCH & LOMB INCORPORATED (US) | 2013-08-01 | — | — | US | disclosed |
| US-8420711-B2 | Mono ethylenically unsaturated polymerizable group containing polycarbosiloxane monomers | BAUSCH & LOMB INCORPORATED (US) | 2013-04-16 | — | — | US | disclosed |
| US-7915323-B2 | Mono ethylenically unsaturated polycarbosiloxane monomers | BAUSCH & LAMB INCORPORATED (US) | 2011-03-29 | — | — | US | disclosed |
| US-20110009519-A1 | MONO ETHYLENICALLY UNSATURATED POLYMERIZABLE GROUP CONTAINING POLYCARBOSILOXANE MONOMERS | SOLTA MEDICAL, INC. | 2011-01-13 | — | — | US | disclosed |