Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 4/20 | 0.31 |
| ▸ | CES1 | P23141 | 4/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7943777 | 0.94 | TSHR (0.32) | CES1ALDH1A1TSHR | |
| SCHEMBL18419462 | 0.85 | ALDH1A1 (0.35) | CES2CES1ALDH1A1TSHR | |
| SCHEMBL6261253 | 0.83 | CES1 (0.32) | CES2CES1ALDH1A1LMNA | |
| SCHEMBL12759296 | 0.82 | — | — | |
| SCHEMBL8361178 | 0.81 | CES2 (0.34) | CES2CES1ALDH1A1TSHRLMNA | |
| SCHEMBL31745691 | 0.81 | CES2 (0.34) | CES2CES1ALDH1A1TSHRLMNA | |
| SCHEMBL12775038 | 0.81 | CES1 (0.31) | CES2CES1 | |
| SCHEMBL10030119 | 0.81 | CES2 (0.31) | CES2CES1 | |
| SCHEMBL465121 | 0.79 | ALDH1A1 (0.37) | CES1ALDH1A1TSHR | |
| SCHEMBL18419461 | 0.79 | CES1 (0.33) | CES2CES1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140046084-A1 | Siloxane Compound and Cured Product Thereof | CENTRAL GLASS COMPANY, LIMITED (JP) | 2014-02-13 | — | — | US | disclosed |
| US-20140046084-A1 | Siloxane Compound and Cured Product Thereof | CENTRAL GLASS COMPANY, LIMITED (JP) | 2014-02-13 | — | — | US | disclosed |