Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15945335 | 0.93 | RARB (0.35) | NPC1RAB9ASMN1; SMN2HSD17B10 | |
| SCHEMBL15945337 | 0.92 | NPC1 (0.33) | NPC1TP53PKMRAB9ASMN1; SMN2 | |
| SCHEMBL15785199 | 0.90 | ALOX5AP (0.35) | NPC1TP53PKMRAB9ASMN1; SMN2 | |
| SCHEMBL12357782 | 0.89 | ALOX5AP (0.37) | NPC1TP53PKMRAB9ASMN1; SMN2 | |
| SCHEMBL19829143 | 0.89 | NPC1 (0.31) | NPC1TP53PKMRAB9ASMN1; SMN2 | |
| SCHEMBL12357209 | 0.88 | ALOX5AP (0.41) | NPC1TP53PKMRAB9ASMN1; SMN2 | |
| SCHEMBL12357793 | 0.88 | ALOX5AP (0.34) | NPC1TP53PKMRAB9ASMN1; SMN2 | |
| SCHEMBL15317560 | 0.88 | NPC1 (0.32) | NPC1TP53PKMRAB9ASMN1; SMN2 | |
| SCHEMBL12760426 | 0.87 | NPC1 (0.36) | NPC1TP53PKMRAB9ASMN1; SMN2 | |
| SCHEMBL12357528 | 0.87 | ALOX5AP (0.39) | NPC1TP53PKMRAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9822305-B2 | Liquid crystal medium and liquid crystal display | MERCK PATENT GMBH (DE) | 2017-11-21 | — | — | US | disclosed |
| US-9809749-B2 | Mesogenic compound, liquid-crystal medium and liquid crystal display | MERCK PATENT GMBH (DE) | 2017-11-07 | — | — | US | disclosed |
| EP-2986688-B1 | MESOGENIC COMPOUND, LIQUID CRYSTAL MEDIUM AND LIQUID CRYSTAL DISPLAY | MERCK PATENT GMBH (DE) | 2017-04-19 | — | — | EP | disclosed |
| US-20160326436-A1 | LIQUID CRYSTAL MEDIUM AND LIQUID CRYSTAL DISPLAY | MERCK PATENT GMBH (DE) | 2016-11-10 | — | — | US | disclosed |
| US-9475990-B2 | Liquid crystal medium and liquid crystal display | MERCK PATENT GMBH (DE) | 2016-10-25 | — | — | US | disclosed |
| EP-2904068-B1 | LIQUID CRYSTAL MEDIUM AND LIQUID CRYSTAL DISPLAY | MERCK PATENT GMBH (DE) | 2016-10-12 | — | — | EP | disclosed |
| EP-2302015-B1 | OPTICALLY ISOTROPIC LIQUID CRYSTALLINE MEDIUM, AND OPTICAL ELEMENT | JNC CORP (JP) | 2016-10-05 | — | — | EP | disclosed |
| US-20160115388-A1 | MESOGENIC COMPOUND, LIQUID-CRYSTAL MEDIUM AND LIQUID CRYSTAL DISPLAY | MERCK PATENT GMBH (DE) | 2016-04-28 | — | — | US | disclosed |
| US-20150247089-A1 | LIQUID CRYSTAL MEDIUM AND LIQUID CRYSTAL DISPLAY | MERCK PATENT GMBH (DE) | 2015-09-03 | — | — | US | disclosed |
| US-9120969-B2 | Liquid crystal medium and liquid crystal display | MERCK PATENT GMBH (DE) | 2015-09-01 | — | — | US | disclosed |
| US-20140158934-A1 | LIQUID CRYSTAL MEDIUM AND LIQUID CRYSTAL DISPLAY | MERCK PATENT GMBH (DE) | 2014-06-12 | — | — | US | disclosed |
| US-20140077130-A1 | LIQUID CRYSTAL MEDIUM AND LIQUID CRYSTAL DISPLAY | MERCK PATENT GMBH (DE) | 2014-03-20 | — | — | US | disclosed |
| US-8659737-B2 | Liquid crystal medium and liquid crystal display | MERCK PATENT GMBH (DE) | 2014-02-25 | — | — | US | disclosed |
| US-8475887-B2 | Optically isotropic liquid crystal medium, and optical device | JNC CORPORATION (JP) | 2013-07-02 | — | — | US | disclosed |
| US-8475887-B2 | Optically isotropic liquid crystal medium, and optical device | JNC CORPORATION (JP) | 2013-07-02 | — | — | US | disclosed |
| EP-2568032-A2 | Liquid crystal medium and liquid crystal display | Merck Patent GmbH (DE) | 2013-03-13 | — | — | EP | disclosed |
| WO-2013017197-A1 | LIQUID CRYSTAL MEDIUM AND LIQUID CRYSTAL DISPLAY | MERCK PATENT GMBH (DE) | 2013-02-07 | — | — | WO | disclosed |
| EP-2302015-A1 | OPTICALLY ISOTROPIC LIQUID CRYSTALLINE MEDIUM, AND OPTICAL ELEMENT | Chisso Corporation (JP) | 2011-03-30 | — | — | EP | disclosed |
| US-20110069245-A1 | OPTICALLY ISOTROPIC LIQUID CRYSTALLINE MEDIUM, AND OPTICAL ELEMENT | CHISSO PETROCHEMICAL CORPORATION (JP) | 2011-03-24 | — | — | US | disclosed |
| US-20110069245-A1 | OPTICALLY ISOTROPIC LIQUID CRYSTALLINE MEDIUM, AND OPTICAL ELEMENT | CHISSO PETROCHEMICAL CORPORATION (JP) | 2011-03-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160115388-A1 | MESOGENIC COMPOUND, LIQUID-CRYSTAL MEDIUM AND LIQUID CRYSTAL DISPLAY | BMP2, IK, EML4 | NPC1 3650/4885TP53 3811/4885PKM 1387/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.