SCHEMBL1276063

SCHEMBL1276063

CCC(=O)C(CCCNC(=N)N)NC(=N)N

nearest known ligand 0.37

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
▸ NPY4R P50391 14/20 0.37
▸ NPY1R P25929 10/20 0.37
▸ NPY5R Q15761 9/20 0.37
▸ NPY2R P49146 6/20 0.37
▸ ALOX15 P16050 1/20 0.35
▸ SIRT6 Q8N6T7 1/20 0.35
▸ SIRT1 Q96EB6 1/20 0.35
▸ MEN1 O00255 2/20 0.34
▸ KMT2A Q03164 2/20 0.34
▸ CYP1A2 P05177 1/20 0.34
▸ SMN1; SMN2 Q16637 1/20 0.34
▸ CHRM2 P08172 1/20 0.33
▸ CHRM4 P08173 1/20 0.33
▸ CHRM1 P11229 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24221401 1.00 NPY4R (0.37) NPY4RNPY1RNPY5RNPY2RALOX15
SCHEMBL20104601 0.86 NPY4R (0.35) NPY4RNPY1RNPY5RNPY2RALOX15
SCHEMBL13131305 0.86 NPY4R (0.35) NPY4RNPY1RNPY5RNPY2RALOX15
SCHEMBL20130678 0.84 NPY4R (0.36) NPY4RNPY1RNPY5RNPY2RALOX15
SCHEMBL18882585 0.84 NPY4R (0.36) NPY4RNPY1RNPY5RNPY2RALOX15
SCHEMBL24157931 0.83 NPY4R (0.40) NPY4RNPY1RNPY5RNPY2RALOX15
SCHEMBL22409687 0.83 NPY4R (0.36) NPY4RNPY1RNPY5RNPY2RALOX15
SCHEMBL14031807 0.83 ALOX15 (0.37) NPY4RNPY1RNPY5RNPY2RALOX15
SCHEMBL29005731 0.81 C3AR1 (0.43) NPY4RNPY1RNPY5RNPY2RALOX15
SCHEMBL12971304 0.81 C3AR1 (0.43) NPY4RNPY1RNPY5RNPY2RALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10415097-B2 Cyanobacteria saxitoxin gene cluster and detection of cyanotoxic organisms NEWSOUTH INNOVATIONS PTY LIMITED (AU) 2019-09-17 — — US disclosed
US-20160153030-A1 CYANOBACTERIA SAXITOXIN GENE CLUSTER AND DETECTION OF CYANOTOXIC ORGANISMS NEWSOUTH INNOVATIONS PTY LIMITED (AU) 2016-06-02 — — US disclosed
EP-2279265-B1 CYANOBACTERIA SAXITOXIN GENE CLUSTER AND DETECTION OF CYANOTOXIC ORGANISMS NEWSOUTH INNOVATIONS PTY LTD (AU) 2014-08-27 — — EP disclosed
US-20110129842-A1 CYANOBACTERIA SAXITOXIN GENE CLUSTER AND DETECTION OF CYANOTOXIC ORGANISMS NEWSOUTH INNOVATIONS PTY LIMITED (AU) 2011-06-02 — — US disclosed
EP-2279265-A1 CYANOBACTERIA SAXITOXIN GENE CLUSTER AND DETECTION OF CYANOTOXIC ORGANISMS NewSouth Innovations Pty Limited (AU) 2011-02-02 — — EP disclosed
WO-2009129558-A1 CYANOBACTERIA SAXITOXIN GENE CLUSTER AND DETECTION OF CYANOTOXIC ORGANISMS NEWSOUTH INNOVATIONS PTY LIMITED (AU) 2009-10-29 — — WO disclosed
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