Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.37 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.35 |
| ▸ | NPY4R | P50391 | 6/20 | 0.35 |
| ▸ | NPY1R | P25929 | 5/20 | 0.35 |
| ▸ | NPY2R | P49146 | 4/20 | 0.35 |
| ▸ | NPY5R | Q15761 | 4/20 | 0.35 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.34 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.34 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.34 |
| ▸ | SPHK1 | Q9NYA1 | 3/20 | 0.33 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.33 |
| ▸ | RRM1 | P23921 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19487474 | 0.85 | NPY4R (0.36) | ALOX15SIRT6SIRT1MEN1KMT2A | |
| SCHEMBL18356744 | 0.84 | ALOX15 (0.39) | ALOX15SIRT6SIRT1MEN1KMT2A | |
| SCHEMBL8663352 | 0.84 | FOLH1 (0.43) | ALOX15SIRT6SIRT1MEN1KMT2A | |
| SCHEMBL19487472 | 0.84 | ALOX15 (0.39) | ALOX15SIRT6SIRT1MEN1KMT2A | |
| SCHEMBL350358 | 0.84 | FOLH1 (0.43) | ALOX15SIRT6SIRT1MEN1KMT2A | |
| SCHEMBL29888878 | 0.84 | FOLH1 (0.43) | ALOX15SIRT6SIRT1MEN1KMT2A | |
| SCHEMBL24221401 | 0.83 | NPY4R (0.37) | ALOX15SIRT6SIRT1MEN1KMT2A | |
| SCHEMBL1276063 | 0.83 | NPY4R (0.37) | ALOX15SIRT6SIRT1MEN1KMT2A | |
| SCHEMBL24531192 | 0.83 | ALOX15 (0.38) | ALOX15SIRT6SIRT1MEN1KMT2A | |
| SCHEMBL17641656 | 0.82 | C3AR1 (0.36) | SIRT6SIRT1MEN1KMT2ADPP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080242838-A1 | LABELING REAGENT AND METHODS OF USE | IRM LLC (BM) | 2008-10-02 | — | — | US | disclosed |
| US-7371514-B2 | Serial derivatization of peptides for de novo sequencing using tandem mass spectrometry | AGILENT TECHNOLOGIES, INC. (US) | 2008-05-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080242838-A1 | LABELING REAGENT AND METHODS OF USE | PTMS, SRMS, DNPEP | ALOX15 4342/4885SIRT6 1032/4885SIRT1 2689/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.