Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | LHCGR | P22888 | 13/20 | 0.49 |
| ▸ | CNR1 | P21554 | 1/20 | 0.43 |
| ▸ | HHAT | Q5VTY9 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2306784 | 0.81 | MAPK1 (0.51) | MAPK1NPSR1LHCGRHHAT | |
| SCHEMBL2305817 | 0.78 | MAPK1 (0.64) | MAPK1NPSR1LHCGRHHAT | |
| SCHEMBL3365428 | 0.77 | LHCGR (0.63) | MAPK1NPSR1LHCGRHHAT | |
| SCHEMBL2312117 | 0.77 | MAPK1 (0.57) | MAPK1NPSR1LHCGRHHAT | |
| SCHEMBL3365920 | 0.76 | MAPK1 (0.66) | MAPK1NPSR1LHCGRHHAT | |
| SCHEMBL2308119 | 0.75 | LHCGR (0.63) | MAPK1NPSR1LHCGR | |
| SCHEMBL2307799 | 0.75 | LHCGR (0.74) | MAPK1NPSR1LHCGRHHAT | |
| SCHEMBL2304864 | 0.74 | MAPK1 (0.62) | MAPK1NPSR1LHCGRHHAT | |
| SCHEMBL2304938 | 0.74 | MAPK1 (0.54) | MAPK1NPSR1LHCGRHHAT | |
| SCHEMBL3366264 | 0.74 | LHCGR (0.55) | MAPK1NPSR1LHCGRHHAT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2350093-B1 | SUBSTITUTED 4,5,6,7-TETRAHYDROTHIENOPYRIDINES AS KCNQ2/3 MODULATORS FOR TREATING PAIN, EPILEPSY AND URINARY INCONTINENCE | GRUENENTHAL GMBH (DE) | 2012-10-03 | — | — | EP | claimed |