Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 4/20 | 0.39 |
| ▸ | CA1 | P00915 | 4/20 | 0.39 |
| ▸ | CA9 | Q16790 | 4/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.37 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.37 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.37 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL984346 | 0.79 | TP53 (0.49) | SMN1; SMN2LMNAMAPTALDH1A1KDM4E | |
| SCHEMBL5346832 | 0.78 | SMN1; SMN2 (0.39) | SMN1; SMN2LMNAKMT2AALDH1A1TP53 | |
| SCHEMBL1520719 | 0.77 | MEN1 (0.50) | CA12CA1CA9SMN1; SMN2MEN1 | |
| SCHEMBL984529 | 0.76 | KMT2A (0.46) | CA12CA1CA9NPSR1SMN1; SMN2 | |
| SCHEMBL1276629 | 0.76 | MAOB (0.46) | CA12CA1CA9SMN1; SMN2ALDH1A1 | |
| SCHEMBL5725738 | 0.76 | SMN1; SMN2 (0.38) | SMN1; SMN2MAPTALDH1A1KDM4ENPC1 | |
| SCHEMBL983385 | 0.76 | TLR4 (0.45) | SMN1; SMN2ALDH1A1TP53CYP3A4TSHR | |
| SCHEMBL767828 | 0.76 | CYP3A4 (0.39) | SMN1; SMN2ALDH1A1TP53CYP3A4TSHR | |
| SCHEMBL7975035 | 0.75 | ALDH1A1 (0.70) | SMN1; SMN2MEN1LMNAMAPTKMT2A | |
| SCHEMBL3078804 | 0.75 | TSHR (0.40) | SMN1; SMN2MAPTALDH1A1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2467020-B1 | SUBSTITUTED ALKYNYL PHENOXY COMPOUNDS AS NEW SYNERGISTS IN PESTICIDAL COMPOSITIONS | ENDURA SPA (IT) | 2014-09-24 | — | — | EP | disclosed |
| US-8809389-B2 | Substituted alkynyl phenoxy compounds as new synergists in pesticidal compositions | ENDURA S.P.A. (IT) | 2014-08-19 | — | — | US | disclosed |
| US-20120208874-A1 | SUBSTITUTED ALKYNYL PHENOXY COMPOUNDS AS NEW SYNERGISTS IN PESTICIDAL COMPOSITIONS | ROTHAMSTED RESEARCH LTD. | 2012-08-16 | — | — | US | disclosed |
| EP-2467020-A1 | SUBSTITUTED ALKYNYL PHENOXY COMPOUNDS AS NEW SYNERGISTS IN PESTICIDAL COMPOSITIONS | Endura S.p.a. (IT) | 2012-06-27 | — | — | EP | disclosed |
| EP-2289889-A1 | Substituted alkynyl phenoxy compounds and their uses | Endura S.p.a. (IT) | 2011-03-02 | — | — | EP | disclosed |
| WO-2011020848-A1 | SUBSTITUTED ALKYNYL PHENOXY COMPOUNDS AS NEW SYNERGISTS IN PESTICIDAL COMPOSITIONS | ENDURA S.P.A. (IT) | 2011-02-24 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120208874-A1 | SUBSTITUTED ALKYNYL PHENOXY COMPOUNDS AS NEW SYNERGISTS IN PESTICIDAL COMPOSITIONS | DDT, PYM1, CHRM1 | CA12 3741/4885CA1 1918/4885CA9 1603/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.