Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 8/20 | 0.46 |
| ▸ | MAOA | P21397 | 5/20 | 0.42 |
| ▸ | CA12 | O43570 | 7/20 | 0.40 |
| ▸ | CA9 | Q16790 | 7/20 | 0.40 |
| ▸ | CA4 | P22748 | 6/20 | 0.40 |
| ▸ | CA1 | P00915 | 2/20 | 0.40 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.40 |
| ▸ | GSTP1 | P09211 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
| ▸ | GMPS | P49915 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | GLA | P06280 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL984346 | 0.80 | TP53 (0.49) | CYP1A2ALDH1A1TSHRTP53CYP3A4 | |
| SCHEMBL5346832 | 0.79 | SMN1; SMN2 (0.39) | ALDH1A1TSHRTP53CYP3A4SMN1; SMN2 | |
| SCHEMBL13338101 | 0.78 | MAOB (0.59) | MAOBMAOACA12CA9CA4 | |
| SCHEMBL5725738 | 0.77 | SMN1; SMN2 (0.38) | MAOBMAOAALDH1A1TSHRTP53 | |
| SCHEMBL767828 | 0.77 | CYP3A4 (0.39) | MAOBALDH1A1TSHRTP53CYP3A4 | |
| SCHEMBL983385 | 0.77 | TLR4 (0.45) | MAOBMAOAALDH1A1TSHRTP53 | |
| SCHEMBL984529 | 0.77 | KMT2A (0.46) | CA12CA9CA1CYP1A2ALDH1A1 | |
| SCHEMBL1276149 | 0.76 | CA12 (0.39) | CA12CA9CA1ALDH1A1TSHR | |
| SCHEMBL981631 | 0.76 | ALDH1A1 (0.40) | CYP1A2ALDH1A1TSHRTP53CYP3A4 | |
| SCHEMBL7975035 | 0.76 | ALDH1A1 (0.70) | CYP1A2ALDH1A1TSHRTP53CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2467020-B1 | SUBSTITUTED ALKYNYL PHENOXY COMPOUNDS AS NEW SYNERGISTS IN PESTICIDAL COMPOSITIONS | ENDURA SPA (IT) | 2014-09-24 | — | — | EP | claimed |
| US-8809389-B2 | Substituted alkynyl phenoxy compounds as new synergists in pesticidal compositions | ENDURA S.P.A. (IT) | 2014-08-19 | — | — | US | claimed |
| US-20120208874-A1 | SUBSTITUTED ALKYNYL PHENOXY COMPOUNDS AS NEW SYNERGISTS IN PESTICIDAL COMPOSITIONS | ROTHAMSTED RESEARCH LTD. | 2012-08-16 | — | — | US | claimed |
| EP-2467020-A1 | SUBSTITUTED ALKYNYL PHENOXY COMPOUNDS AS NEW SYNERGISTS IN PESTICIDAL COMPOSITIONS | Endura S.p.a. (IT) | 2012-06-27 | — | — | EP | claimed |
| EP-2289889-A1 | Substituted alkynyl phenoxy compounds and their uses | Endura S.p.a. (IT) | 2011-03-02 | — | — | EP | claimed |
| WO-2011020848-A1 | SUBSTITUTED ALKYNYL PHENOXY COMPOUNDS AS NEW SYNERGISTS IN PESTICIDAL COMPOSITIONS | ENDURA S.P.A. (IT) | 2011-02-24 | — | — | WO | claimed |
| CN-102480948-B | Substituted alkynyl phenoxy compounds as novel synergists in pesticidal compositions | ENDURA S.P.A. (IT) | 2014-10-29 | — | — | CN | disclosed |
| EP-2467020-B1 | SUBSTITUTED ALKYNYL PHENOXY COMPOUNDS AS NEW SYNERGISTS IN PESTICIDAL COMPOSITIONS | ENDURA SPA (IT) | 2014-09-24 | — | — | EP | disclosed |
| US-8809389-B2 | Substituted alkynyl phenoxy compounds as new synergists in pesticidal compositions | ENDURA S.P.A. (IT) | 2014-08-19 | — | — | US | disclosed |
| US-8809389-B2 | Substituted alkynyl phenoxy compounds as new synergists in pesticidal compositions | ENDURA S.P.A. (IT) | 2014-08-19 | — | — | US | disclosed |
| US-20120208874-A1 | SUBSTITUTED ALKYNYL PHENOXY COMPOUNDS AS NEW SYNERGISTS IN PESTICIDAL COMPOSITIONS | ROTHAMSTED RESEARCH LTD. | 2012-08-16 | — | — | US | disclosed |
| US-20120208874-A1 | SUBSTITUTED ALKYNYL PHENOXY COMPOUNDS AS NEW SYNERGISTS IN PESTICIDAL COMPOSITIONS | ROTHAMSTED RESEARCH LTD. | 2012-08-16 | — | — | US | disclosed |
| EP-2467020-A1 | SUBSTITUTED ALKYNYL PHENOXY COMPOUNDS AS NEW SYNERGISTS IN PESTICIDAL COMPOSITIONS | Endura S.p.a. (IT) | 2012-06-27 | — | — | EP | disclosed |
| EP-2467020-A1 | SUBSTITUTED ALKYNYL PHENOXY COMPOUNDS AS NEW SYNERGISTS IN PESTICIDAL COMPOSITIONS | Endura S.p.a. (IT) | 2012-06-27 | — | — | EP | disclosed |
| CN-102480948-A | Substituted alkynyl phenoxy compounds as novel synergists in pesticidal compositions | ENDURA SPA | 2012-05-30 | — | — | CN | disclosed |
| EP-2289889-A1 | Substituted alkynyl phenoxy compounds and their uses | Endura S.p.a. (IT) | 2011-03-02 | — | — | EP | disclosed |
| EP-2289889-A1 | Substituted alkynyl phenoxy compounds and their uses | Endura S.p.a. (IT) | 2011-03-02 | — | — | EP | disclosed |
| WO-2011020848-A1 | SUBSTITUTED ALKYNYL PHENOXY COMPOUNDS AS NEW SYNERGISTS IN PESTICIDAL COMPOSITIONS | ENDURA S.P.A. (IT) | 2011-02-24 | — | — | WO | disclosed |
| WO-2011020848-A1 | SUBSTITUTED ALKYNYL PHENOXY COMPOUNDS AS NEW SYNERGISTS IN PESTICIDAL COMPOSITIONS | ENDURA S.P.A. (IT) | 2011-02-24 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120208874-A1 | SUBSTITUTED ALKYNYL PHENOXY COMPOUNDS AS NEW SYNERGISTS IN PESTICIDAL COMPOSITIONS | DDT, PYM1, CHRM1 | MAOB 564/4885MAOA 849/4885CA12 3741/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.