SCHEMBL127619

SCHEMBL127619

Nc1ccc2c(c1)NCCO2

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GAA P10253 5/20 0.62
MAPT P10636 4/20 0.62
ALDH1A1 P00352 2/20 0.62
HSD17B10 Q99714 2/20 0.62
KDM4E B2RXH2 3/20 0.47
PDE3B Q13370 2/20 0.46
PDE3A Q14432 2/20 0.46
PRKCI P41743 1/20 0.43
BRD4 O60885 1/20 0.42
FABP6 P51161 1/20 0.40
GLA P06280 1/20 0.39
HPGD P15428 1/20 0.39
CASP1 P29466 1/20 0.39
CASP7 P55210 1/20 0.39
ATM Q13315 1/20 0.39
TRPV1 Q8NER1 1/20 0.37
AR P10275 1/20 0.36
PTGER3 P43115 1/20 0.35
SMN1; SMN2 Q16637 2/20 0.35
NPC1 O15118 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30343092 1.00 GAA (0.62) GAAMAPTALDH1A1HSD17B10KDM4E
Hydrochloric Acid SCHEMBL6164775 0.98 GAA (0.61) GAAMAPTALDH1A1HSD17B10KDM4E
Hydrochloric Acid SCHEMBL6550641 0.98 GAA (0.61) GAAMAPTALDH1A1HSD17B10KDM4E
SCHEMBL6373230 0.89 MAPT (0.50) GAAMAPTALDH1A1HSD17B10KDM4E
SCHEMBL3588662 0.85 GAA (0.49) GAAMAPTALDH1A1HSD17B10KDM4E
Hydrochloric Acid SCHEMBL17505046 0.81 GAA (0.49) GAAMAPTALDH1A1HSD17B10KDM4E
SCHEMBL2717534 0.80 MAPT (0.41) GAAMAPTALDH1A1HSD17B10KDM4E
SCHEMBL304035 0.77 ALDH1A1 (0.62) GAAMAPTALDH1A1HSD17B10KDM4E
SCHEMBL2933658 0.77 ALDH1A1 (1.00) GAAMAPTALDH1A1HSD17B10KDM4E
SCHEMBL33867 0.77 ALDH1A1 (0.62) GAAMAPTALDH1A1HSD17B10KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 2294 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4608363-A1 A COMPOSITION FOR IMPROVING EFFECTIVENESS OF DYE PRECURSORS FOR CHANGE OF COLOUR OF HAIR Cavinkare Pvt. Ltd (IN) 2025-09-03 EP claimed
WO-2025099111-A1 NEW TELESCOPING SYNTHESES OF 6-HYDROXY-BENZOMORPHOLINE (3,4-DIHYDRO-2H-1,4-BENZOXAZIN-6-OL) WELLA GERMANY GMBH (DE) 2025-05-15 WO claimed
WO-2024170772-A1 EPIGALLOCATECHIN-3-GALLATE (EGCG) ANALOGS FOR USE IN THE TREATMENT OF DISEASES IN WHICH AN INCREASE OF NAD+ IS BENEFICIAL SUCH AS GLAUCOMA MIM NEUROSCIENCES AB (SE) 2024-08-22 WO claimed
WO-2024089704-A1 A COMPOSITION FOR IMPROVING EFFECTIVENESS OF DYE PRECURSORS FOR CHANGE OF COLOUR OF HAIR CAVINKARE PVT.LTD. (IN) 2024-05-02 WO claimed
WO-2014202150-A1 NEW CATIONIC DYES, KITS AND COMPOSITIONS THEREOF, AND PROCESS FOR DYEING KERATIN FIBERS ALFA PARF GROUP S.P.A. (IT) 2014-12-24 WO claimed
US-8043385-B2 Composition oxidation colouring of keratinic fibres, containing a cationic cellulose ether, a metasilicate and oxidation dyes, method for oxidation colouring and uses thereof L'OREAL S.A. (FR) 2011-10-25 US claimed
JP-4785024-B2 2011-10-05 JP claimed
US-8002847-B2 Composition for oxidation dyeing keratin fibres comprising a cationic cellulose ether, a weakly oxyethylenated sorbitan fatty acid ester and oxidation dyes L 'OREAL S.A. (FR) 2011-08-23 US claimed
US-20100275388-A1 COMPOSITION FOR OXIDATION DYEING KERATIN FIBRES COMPRISING A CATIONIC CELLULOSE ETHER, A WEAKLY OXYETHYLENATED SORBITAN FATTY ACID ESTER AND OXIDATION DYES L'OREAL S.A. (FR) 2010-11-04 US claimed
US-20100263138-A1 COMPOSITION OXIDATION COLOURING OF KERATINIC FIBRES, CONTAINING A CATIONIC CELLULOSE ETHER, A METASILICATE AND OXIDATION DYES, METHOD FOR OXIDATION COLOURING AND USES THEREOF L'OREAL S.A. (FR) 2010-10-21 US claimed
EP-0424261-A1 Dyeing composition containing oxidation dyes precursors and aminoindole derivatives as coupling agent L'OREAL (FR) 1991-04-24 EP claimed
US-4985955-A INTENSE COLORATIONS IN RELATIVELY SHORT TIMES L'OREAL (FR) 1991-01-22 US claimed
US-4979961-A p-phenylenediamines, process for preparation thereof, dyeing composition containing them and corresponding dyeing process L'OREAL (FR) 1990-12-25 US claimed
US-4904275-A OXIDIZER L'OREAL (FR) 1990-02-27 US claimed
US-4692166-A OXIDATION COLOR DYES USED WITH DIAMINOBENZENES OR AMINO PHENOLS; MINIMIZATION OF RED HUE L'OREAL (FR) 1987-09-08 US claimed
US-4563188-A SHADES OF GREEN L'OREAL (FR) 1986-01-07 US claimed
US-4425132-A HAIR DYES, APPLYING WITHOUT RINSING L'OREAL (FR) 1984-01-10 US claimed
US-4323360-A Dyeing compositions for hair which contain 2,4-diamino-butoxybenzene and/or a salt thereof as the coupling agent L'OREAL (FR) 1982-04-06 US claimed
US-4289495-A HAIR DYES, STORAGE STABILITY L'OREAL (FR) 1981-09-15 US claimed
US-4149848-A N-/TETRAHYDROFURFURYL/P-PHENYLENEDIAMINES L'OREAL (FR) 1979-04-17 US claimed