Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ASGR1 | P07306 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8581103 | 0.89 | ASGR1 (0.33) | ASGR1ALDH1A1L3MBTL1 | |
| SCHEMBL5179161 | 0.89 | ASGR1 (0.33) | ASGR1ALDH1A1L3MBTL1 | |
| SCHEMBL7136442 | 0.89 | ASGR1 (0.33) | ASGR1ALDH1A1L3MBTL1 | |
| SCHEMBL12560770 | 0.88 | MAPK1 (0.40) | ASGR1ALDH1A1L3MBTL1PKMCA1 | |
| SCHEMBL12601164 | 0.86 | ASGR1 (0.33) | ASGR1ALDH1A1L3MBTL1PKM | |
| SCHEMBL1743867 | 0.79 | — | — | |
| SCHEMBL2803932 | 0.79 | — | — | |
| SCHEMBL14542000 | 0.78 | MAPK1 (0.51) | ASGR1ALDH1A1L3MBTL1PKMMAPK1 | |
| SCHEMBL10042138 | 0.77 | L3MBTL1 (0.30) | L3MBTL1 | |
| SCHEMBL16135488 | 0.77 | MAPK1 (0.39) | ASGR1ALDH1A1L3MBTL1PKMCA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7906633-B2 | Reagents and methods for preparing LPS antagonist B1287 and stereoisomers thereof | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2011-03-15 | — | — | US | disclosed |