⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1743867 | 1.00 | — | — | |
| SCHEMBL8581103 | 0.90 | ASGR1 (0.33) | — | |
| SCHEMBL5179161 | 0.90 | ASGR1 (0.33) | — | |
| SCHEMBL7136442 | 0.90 | ASGR1 (0.33) | — | |
| SCHEMBL7889397 | 0.89 | ALDH1A1 (0.36) | — | |
| SCHEMBL7567193 | 0.89 | ALDH1A1 (0.36) | — | |
| SCHEMBL7886992 | 0.89 | ALDH1A1 (0.36) | — | |
| SCHEMBL2804057 | 0.88 | — | — | |
| SCHEMBL9786210 | 0.87 | ALDH1A1 (0.32) | — | |
| SCHEMBL9786206 | 0.86 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150050282-A1 | GLYCOCONJUGATES AND USE THEREOF AS VACCINE AGAINST SHIGELLA FLEXNERI SEROTYPE 3a AND X | INSTITUT PASTEUR (FR) | 2015-02-19 | — | — | US | claimed |
| US-20100239584-A1 | GLYCOCONJUGATES AND USE THEREOF AS VACCINE AGAINST SHIGELLA FLEXNERI SEROTYPE 3A AND X | INSTITUT PASTEUR (FR) | 2010-09-23 | — | — | US | claimed |
| US-10087242-B2 | Glycoconjugates and use thereof as vaccine against Shigella flexneri serotype 3a and X | INSTITUT PASTEUR (FR) | 2018-10-02 | — | — | US | disclosed |
| EP-2164521-B1 | GLYCOCONJUGATES AND USE THEREOF AS VACCINE AGAINST SHIGELLA FLEXNERI SEROTYPE 3A AND X | PASTEUR INSTITUT (FR) | 2018-09-12 | — | — | EP | disclosed |
| US-20150050282-A1 | GLYCOCONJUGATES AND USE THEREOF AS VACCINE AGAINST SHIGELLA FLEXNERI SEROTYPE 3a AND X | INSTITUT PASTEUR (FR) | 2015-02-19 | — | — | US | disclosed |
| US-8815239-B2 | Glycoconjugates and use thereof as vaccine against Shigella flexneri serotype 3a and X | INSTITUT PASTEUR (FR) | 2014-08-26 | — | — | US | disclosed |
| US-20100239584-A1 | GLYCOCONJUGATES AND USE THEREOF AS VACCINE AGAINST SHIGELLA FLEXNERI SEROTYPE 3A AND X | INSTITUT PASTEUR (FR) | 2010-09-23 | — | — | US | disclosed |
| EP-2164521-A2 | GLYCOCONJUGATES AND USE THEREOF AS VACCINE AGAINST<I>SHIGELLA FLEXNERI</I>SEROTYPE 3A AND X | Institut Pasteur (FR) | 2010-03-24 | — | — | EP | disclosed |
| WO-2008155487-A2 | GLYCOCONJUGATES AND USE THEREOF AS VACCINE AGAINST SHIGELLA FLEXNERI SEROTYPE 3A AND X | INSTITUT PASTEUR (FR) | 2008-12-24 | — | — | WO | disclosed |