Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | APAF1 | O14727 | 1/20 | 0.34 |
| ▸ | MITF | O75030 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | HTR1B | P28222 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | ALPL | P05186 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1276339 | 0.87 | INPPL1 (0.47) | MAPTLMNAHTTGAAMAPK1 | |
| SCHEMBL15811767 | 0.85 | MAPT (0.42) | MAPTLMNAHTTGAAMAPK1 | |
| SCHEMBL108985 | 0.80 | MAPT (0.71) | MAPTLMNAHTTGAAMAPK1 | |
| SCHEMBL8153933 | 0.79 | MAPT (0.47) | MAPTLMNAHTTGAAMAPK1 | |
| SCHEMBL6814025 | 0.75 | MAPT (0.65) | MAPTLMNAHTTGAAMAPK1 | |
| SCHEMBL3873601 | 0.73 | INPPL1 (0.50) | MAPTLMNAHTTGAAMAPK1 | |
| SCHEMBL28975675 | 0.73 | MAPT (0.43) | MAPTLMNAHTTGAAMAPK1 | |
| SCHEMBL15811768 | 0.72 | INPPL1 (0.49) | MAPTLMNAHTTGAAMAPK1 | |
| SCHEMBL1192357 | 0.72 | L3MBTL1 (0.37) | MAPTHTTGAANPSR1GPR84 | |
| SCHEMBL29405980 | 0.72 | KDM4E (0.50) | MAPTLMNAHTTGAAMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8759411-B2 | Derivatives of diphosphines as flame retardants for polyurethanes | BASF SE (DE) | 2014-06-24 | — | — | US | disclosed |
| US-8519035-B2 | Cyclic phosphines as flame retardants | BASF SE (DE) | 2013-08-27 | — | — | US | disclosed |
| US-20120251810-A1 | Derivatives of diphosphines as flame retardants in aromatic and/or heteroaromatic epoxy resins | BASF SE (DE) | 2012-10-04 | — | — | US | disclosed |
| US-20110263764-A1 | CYCLIC PHOSPHINES AS FLAME RETARDANTS | BASF SE (DE) | 2011-10-27 | — | — | US | disclosed |
| US-20110190407-A1 | DERIVATIVES OF DIPHOSPHINES AS FLAME RETARDANTS FOR POLYURETHANES | BASF SE (DE) | 2011-08-04 | — | — | US | disclosed |
| US-20110028603-A1 | HYPERBRANCHED POLYMERS AND OLIGOMERS COMPRISING TERMINAL AMINO GROUPS AS CURING AGENTS FOR EPOXY RESINS | BASF SE (DE) | 2011-02-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110263764-A1 | CYCLIC PHOSPHINES AS FLAME RETARDANTS | PFAS, PHOSPHO1, PLCG2 | MAPT 4119/4885LMNA 3812/4885HTT 3411/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.