Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 8/20 | 0.44 |
| ▸ | ESR2 | Q92731 | 5/20 | 0.44 |
| ▸ | AR | P10275 | 3/20 | 0.44 |
| ▸ | VDR | P11473 | 10/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1524176 | 0.90 | ESR1 (0.57) | ESR1ESR2ARVDR | |
| SCHEMBL1524180 | 0.90 | ESR1 (0.57) | ESR1ESR2ARVDR | |
| SCHEMBL12764233 | 0.90 | ESR1 (0.45) | ESR1ESR2ARVDRHDAC3 | |
| SCHEMBL12764486 | 0.88 | ESR1 (0.44) | ESR1ESR2ARVDR | |
| SCHEMBL1524862 | 0.87 | ESR1 (0.56) | ESR1ESR2ARVDR | |
| SCHEMBL1525163 | 0.87 | ESR1 (0.63) | ESR1ESR2ARVDR | |
| SCHEMBL1525162 | 0.87 | ESR1 (0.63) | ESR1ESR2ARVDR | |
| SCHEMBL1524865 | 0.87 | ESR1 (0.56) | ESR1ESR2ARVDR | |
| SCHEMBL5158963 | 0.83 | ESR1 (0.39) | ESR1ESR2ARVDRHDAC3 | |
| SCHEMBL5158971 | 0.83 | ESR1 (0.39) | ESR1ESR2ARVDRHDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110060146-A1 | VITAMIN-D-LIKE COMPOUNDS | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2011-03-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110060146-A1 | VITAMIN-D-LIKE COMPOUNDS | VDR, CYP24A1, CYP2R1 | ESR1 1899/4885ESR2 2002/4885AR 35/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.