SCHEMBL1276486

SCHEMBL1276486

NC(O)=S.OC(=S)Nc1ccccc1

nearest known ligand 0.70

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.70
TAS2R38 P59533 3/20 0.70
HSD17B10 Q99714 2/20 0.70
TP53 P04637 2/20 0.70
TSHR P16473 2/20 0.70
TYR P14679 1/20 0.70
CYP3A4 P08684 1/20 0.61
GAA P10253 7/20 0.57
KMT2A Q03164 4/20 0.56
RAB9A P51151 3/20 0.56
MEN1 O00255 2/20 0.56
NPC1 O15118 2/20 0.56
NOX1 Q9Y5S8 2/20 0.56
PHGDH O43175 1/20 0.54
MAPT P10636 3/20 0.54
LMNA P02545 3/20 0.50
MAOA P21397 2/20 0.50
MAOB P27338 2/20 0.50
GFER P55789 1/20 0.48
GRIN2D O15399 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28388940 0.98 ALDH1A1 (0.67) ALDH1A1TAS2R38HSD17B10TP53TSHR
Ammonia Solution, Strong SCHEMBL9168287 0.98 ALDH1A1 (0.67) ALDH1A1TAS2R38HSD17B10TP53TSHR
Methane SCHEMBL1286316 0.98 ALDH1A1 (0.67) ALDH1A1TAS2R38HSD17B10TP53TSHR
Methane SCHEMBL9753979 0.95 ALDH1A1 (0.64) ALDH1A1TAS2R38HSD17B10TP53TSHR
Ethane SCHEMBL3723781 0.95 TAS2R38 (0.64) ALDH1A1TAS2R38HSD17B10TP53TSHR
Methane SCHEMBL11774994 0.95 ALDH1A1 (0.64) ALDH1A1TAS2R38HSD17B10TP53TSHR
Ethane SCHEMBL28688723 0.93 TAS2R38 (0.61) ALDH1A1TAS2R38HSD17B10TP53TSHR
Dimethylamine SCHEMBL11568529 0.93 TAS2R38 (0.61) ALDH1A1TAS2R38HSD17B10TP53TSHR
SCHEMBL1936559 0.92 ALDH1A1 (0.70) ALDH1A1TAS2R38HSD17B10TP53TSHR
Hydrochloric Acid SCHEMBL11243942 0.90 ALDH1A1 (0.67) ALDH1A1TAS2R38HSD17B10TP53TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 74 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0713983-B1 Toothed belt TSUBAKIMOTO CHAIN CO (JP) 2002-02-20 EP claimed
US-4524185-A Halogen-containing elastomer composition, and vulcanizing process using dimercaptothiodiazole and dithiocarbamate curing system FEDERAL-MOGUL CORPORATION (US) 1985-06-18 US claimed
EP-3694951-B1 SEMICONDUCTING LIGHT EMITTING MATERIAL MERCK PATENT GMBH (DE) 2023-12-13 EP disclosed
EP-4259856-A1 SILVER-BISMUTH ELECTROLYTE FOR SEPARATING HARD SILVER LAYERS Umicore Galvanotechnik GmbH (DE) 2023-10-18 EP disclosed
WO-2023106192-A1 RUBBER COMPOSITION FOR VEHICLE COOLANT TRANSPORT HOSE, AND VEHICLE COOLANT TRANSPORT HOSE OBTAINED USING SAME 住友理工株式会社 2023-06-15 WO disclosed
CN-116103046-A Quantum dot film, quantum dot light-emitting diode, preparation method of quantum dot light-emitting diode and display device TCL科技集团股份有限公司 2023-05-12 CN disclosed
WO-2023067265-A1 METHOD FOR PREPARING A RUBBER COMPOSITION COMPAGNIE GENERALE DES ETABLISSEMENTS MICHELIN (FR) 2023-04-27 WO disclosed
CN-116003345-A Process method for synthesizing rubber accelerator MBT at normal pressure 山东尚舜化工有限公司 2023-04-25 CN disclosed
US-11608394-B2 Nanoparticles and formulations for printing YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM LTD. (IL) 2023-03-21 US disclosed
WO-2021215380-A1 CARBOXYL GROUP-CONTAINING CROSSLINKED POLYMER OR SALT THEREOF, AND USE THEREOF 東亞合成株式会社 (JP) 2021-10-28 WO disclosed
WO-2021215381-A1 METHOD FOR PRODUCING CARBOXYL GROUP-CONTAINING CROSSLINKED POLYMER OR SALT THEREOF 東亞合成株式会社 (JP) 2021-10-28 WO disclosed
US-4315027-A INSECTICIDES THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 1982-02-09 US disclosed
US-4315026-A INSECTICIDES THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 1982-02-09 US disclosed
US-4298527-A REACTION OF A MERCAPTAN WITH AN N-CHLOROSULFINYLCARBAMATE ESTER THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 1981-11-03 US disclosed
US-4298617-A INSECTICIDES REGENTS OF UNIVERSITY OF CALIFORNIA (US) 1981-11-03 US disclosed
US-4263318-A INSECTICIDES THE REAGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 1981-04-21 US disclosed
US-4262015-A INSECTICIDES THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 1981-04-14 US disclosed
US-4256858-A CROSSLINKING AGENTS FOR NEOPRENE ARE 2,2,4-TRIMETHYL-1,2-DIHYDROQUINOLINE AND INDOLE, ACRIDANE, CARBAZOLE, ISOQUINOLINE AND QUINOLINE DERIVATIVES; UNIFORM VULCANIZATION TIMES BAYER AKTIENGESELLSCHAFT (DE) 1981-03-17 US disclosed
EP-0016590-A1 N-Sulfinyl carbamates, their use as pesticides, pesticidal compositions containing them, methods of producing them and halosulfinyl carbamates formed during their production THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 1980-10-01 EP disclosed
US-4060628-A 2-(Alkylhalophenylimino)dithiolanes and ectoparasiticidal composition and method BAYER AKTIENGESELLSCHAFT (DT) 1977-11-29 US disclosed