Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | CCNE1 | P24864 | 11/20 | 0.35 |
| ▸ | CDK2 | P24941 | 11/20 | 0.35 |
| ▸ | CCND1 | P24385 | 7/20 | 0.34 |
| ▸ | CDK6 | Q00534 | 7/20 | 0.34 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22686926 | 0.88 | TP53 (0.38) | MAPK1ATMHSD11B1TP53CCNE1 | |
| SCHEMBL12765358 | 0.88 | TP53 (0.38) | MAPK1ATMHSD11B1TP53CCNE1 | |
| SCHEMBL14971519 | 0.80 | MEN1 (0.44) | MAPK1TSHRL3MBTL1 | |
| SCHEMBL2424959 | 0.78 | CCNE1 (0.33) | TP53CCNE1CDK2CCND1CDK6 | |
| SCHEMBL12765346 | 0.78 | — | — | |
| SCHEMBL15543574 | 0.78 | TSHR (0.51) | ATMTP53TSHRGAA | |
| SCHEMBL21885829 | 0.78 | HSD11B1 (0.38) | MAPK1ATMHSD11B1TP53TSHR | |
| SCHEMBL12765351 | 0.77 | TP53 (0.31) | TP53 | |
| Hydrochloric Acid SCHEMBL31722161 | 0.77 | GNAI3 (0.32) | TP53CCNE1CDK2CCND1CDK6 | |
| SCHEMBL12765364 | 0.76 | TSHR (0.41) | MAPK1HSD11B1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114206893-A | (hetero) aryl-methyl-thio-beta-D-galactopyranoside derivatives | 爱杜西亚药品有限公司 | 2022-03-18 | — | — | CN | claimed |
| EP-4010076-B1 | (HETERO)ARYL-METHYL-THIO-BETA-D-GALACTOPYRANOSIDE DERIVATIVES | IDORSIA PHARMACEUTICALS LTD (CH) | 2024-01-17 | — | — | EP | disclosed |
| CN-114206893-A | (hetero) aryl-methyl-thio-beta-D-galactopyranoside derivatives | 爱杜西亚药品有限公司 | 2022-03-18 | — | — | CN | disclosed |
| US-7902203-B2 | Anti-infective agents | ABBOTT LABORATORIES, INC. (US) | 2011-03-08 | — | — | US | disclosed |