SCHEMBL1276646

SCHEMBL1276646

CC(C)CC(C)NCC1(C)CC(NC(C)CC(C)C)CC(C)(C)C1

nearest known ligand 0.38

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18817828 0.83 TSHR (0.38) TSHR
SCHEMBL8017275 0.80 TSHR (0.30) TSHR
Ammonia Solution, Strong SCHEMBL8026093 0.79
SCHEMBL118304 0.78 TSHR (0.41) TSHR
Ammonia Solution, Strong SCHEMBL19024280 0.76 TSHR (0.40) TSHR
SCHEMBL1276143 0.75 TSHR (0.39) TSHR
SCHEMBL17703945 0.71 TSHR (0.41) TSHR
SCHEMBL3115954 0.70 TSHR (0.38) TSHR
SCHEMBL2122692 0.67 TSHR (0.40) TSHR
SCHEMBL4552065 0.67 TSHR (0.38) TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-2011504197-A 2011-02-03 JP claimed
US-20100273008-A1 POLYURETHANE POLYMER FOR REVERSIBLE ADHESIVE BONDS SIKA TECHNOLOGY AG (CH) 2010-10-28 US claimed
WO-2009065913-A1 POLYURETHANE POLYMER FOR REVERSIBLE ADHESIVE BONDS SIKA TECHNOLOGY AG (CH) 2009-05-28 WO claimed
EP-2062926-A1 Polyurethane polymer for reversible adhesive joints Sika Technology AG (CH) 2009-05-27 EP claimed
EP-2143707-B1 Secondary diamine LINE X LLC (US) 2018-04-11 EP disclosed
US-8212078-B2 Making chain extenders with slower cure rates; reacting a ketone and/or aldehyde with a primary amine in the presence of an acidic ion exchange resin and hydrogenation agent; making diimine same way but excluding hydrogenation agent; e.g. N,N'-di-5-nonyl-isophoronediamine ALBEMARLE CORPORATION (US) 2012-07-03 US disclosed
US-20100273008-A1 POLYURETHANE POLYMER FOR REVERSIBLE ADHESIVE BONDS SIKA TECHNOLOGY AG (CH) 2010-10-28 US disclosed
EP-2143707-A2 Secondary diamine Albermarle Corporation (US) 2010-01-13 EP disclosed
WO-2009065913-A1 POLYURETHANE POLYMER FOR REVERSIBLE ADHESIVE BONDS SIKA TECHNOLOGY AG (CH) 2009-05-28 WO disclosed
EP-2062926-A1 Polyurethane polymer for reversible adhesive joints Sika Technology AG (CH) 2009-05-27 EP disclosed
US-20080194788-A1 Diimines and Secondary Diamines ALBEMARLE CORPORATION (US) 2008-08-14 US disclosed
EP-1868987-A1 DIIMINES AND SECONDARY DIAMINES ALBEMARLE CORPORATION (US) 2007-12-26 EP disclosed
WO-2006104528-A1 DIIMINES AND SECONDARY DIAMINES ALBEMARLE CORPORATION (US) 2006-10-05 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080194788-A1 Diimines and Secondary Diamines DDT, DDC, AOC1 TSHR 2793/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.