⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14536622 | 1.00 | — | — | |
| SCHEMBL21676970 | 0.81 | — | — | |
| SCHEMBL17189497 | 0.81 | — | — | |
| SCHEMBL12555028 | 0.78 | — | — | |
| SCHEMBL994559 | 0.77 | — | — | |
| SCHEMBL8080972 | 0.74 | — | — | |
| SCHEMBL11587168 | 0.73 | PAX8 (0.31) | — | |
| SCHEMBL8528219 | 0.73 | PAX8 (0.31) | — | |
| SCHEMBL11375580 | 0.73 | PAX8 (0.31) | — | |
| SCHEMBL30685396 | 0.73 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 180 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210317235-A1 | METHODS AND SYSTEMS FOR POLYMER PRECIPITATION AND GENERATION OF PARTICLES | NOVARTIS AG (CH) | 2021-10-14 | — | — | US | disclosed |
| US-20210128516-A1 | CYCLODEXTRIN-BASED POLYMERS FOR DELIVERING THE THERAPEUTIC AGENTS COVALENTLY BOUND THERETO | NOVARTIS AG (CH) | 2021-05-06 | — | — | US | disclosed |
| US-20200323889-A1 | CYCLODEXTRIN-BASED POLYMERS FOR THERAPEUTIC DELIVERY | CERULEAN PHARMA INC. | 2020-10-15 | — | — | US | disclosed |
| US-20200046845-A1 | CYCLODEXTRIN-BASED POLYMERS FOR THERAPEUTIC DELIVERY | CERULEAN PHARMA INC. | 2020-02-13 | — | — | US | disclosed |
| EP-3566719-A1 | COMPOSITIONS AND METHODS FOR TREATMENT OF AUTOIMMUNE AND OTHER DISEASES | Cerulean Pharma Inc. (US) | 2019-11-13 | — | — | EP | disclosed |
| US-20180193486-A1 | COMPOSITIONS AND METHODS FOR TREATMENT OF AUTOIMMUNE AND OTHER DISEASE | CERULEAN PHARMA INC. | 2018-07-12 | — | — | US | disclosed |
| EP-3332811-A1 | CYCLODEXTRIN-BASED POLYMERS FOR DELIVERING COVALENTLY ATTACHED CAMPTOTHECIN | Cerulean Pharma Inc. (US) | 2018-06-13 | — | — | EP | disclosed |
| US-20180110791-A1 | CYCLODEXTRIN-BASED POLYMERS FOR THERAPEUTIC DELIVERY | CERULEAN PHARMA INC. | 2018-04-26 | — | — | US | disclosed |
| EP-2402036-B1 | Cyclodextrin-based polymers for delivering the therapeutic agents covalently attached thereto | CERULEAN PHARMA INC (US) | 2018-02-14 | — | — | EP | disclosed |
| US-20180030207-A1 | LINEAR CYCLODEXTRIN COPOLYMERS | CALIFORNIA INSTITUTE OF TECHNOLOGY | 2018-02-01 | — | — | US | disclosed |
| US-20080058427-A1 | Cyclodextrin-based polymers for therapeutics delivery | INSERT THERAPEUTICS, INC. (US) | 2008-03-06 | — | — | US | disclosed |
| US-7270808-B2 | Having covalently coupled bioactive agent and targeting ligand; controlled release; stability, solubility; reduced toxicity | INSERT THERAPEUTICS, INC. (US) | 2007-09-18 | — | — | US | disclosed |
| US-7270808-B2 | Having covalently coupled bioactive agent and targeting ligand; controlled release; stability, solubility; reduced toxicity | INSERT THERAPEUTICS, INC. (US) | 2007-09-18 | — | — | US | disclosed |
| US-20070128167-A1 | Complexing agents for compositions containing inclusion complexes | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 2007-06-07 | — | — | US | disclosed |
| US-20070128167-A1 | Complexing agents for compositions containing inclusion complexes | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 2007-06-07 | — | — | US | disclosed |
| EP-1764112-A2 | Linear cyclodextrin copolymers | California Institute of Technology (US) | 2007-03-21 | — | — | EP | disclosed |
| EP-1133318-B1 | SUPRAMOLECULAR COMPLEXES CONTAINING THERAPEUTIC AGENTS | CALIFORNIA INST OF TECHN (US) | 2007-03-14 | — | — | EP | disclosed |
| US-20070025952-A1 | Linear cyclodextrin copolymers | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 2007-02-01 | — | — | US | disclosed |
| US-20070025952-A1 | Linear cyclodextrin copolymers | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 2007-02-01 | — | — | US | disclosed |
| US-7166302-B2 | Complexing agents for compositions containing inclusion complexes | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 2007-01-23 | — | — | US | disclosed |